Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Hydrochlorothiazide is dosed at 1–4 mg/kg PO q12h in rabbits, per van Zeeland YR.A, Schoemaker NJ. Diagnosis and treatment of cardiovascular disease in small mammals. Proc Conf Annu Assoc Exot Mam Vet; 2018:607-616. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.872 (2026-08-01, PENDING REVIEW). Hydrochlorothiazide is used in rabbits for Diuretic. Routes documented in rabbits: PO. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Hydrochlorothiazide in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: HydroDiuril, Microzide
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 1–4 mg/kg | q12h | Diuretic | Moderate | van Zeeland YR.A, Schoemaker NJ. Diagnosis and treatment of cardiovascular disease in small mammals. Proc Conf Annu Assoc Exot Mam Vet; 2018:607-616. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.872 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your rabbit's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits sodium-chloride cotransporter in distal convoluted tubule. Reduces renal calcium excretion (useful in calcium oxalate stone prevention).
Hypokalemia, hyponatremia risk. Monitor electrolytes. Less potent diuretic than furosemide. Used with furosemide for diuretic resistance.
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Hydrochlorothiazide dose range in rabbits, with cited source references: PO 1–4 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Hydrochlorothiazide in rabbits: PO.
Hydrochlorothiazide is indicated in rabbits for: Diuretic.
These are general warnings for Hydrochlorothiazide across species; consult the rabbit dosing table above for species-specific guidance. Hypokalemia, hyponatremia risk. Monitor electrolytes. Less potent diuretic than furosemide. Used with furosemide for diuretic resistance.
Why a species-specific page? Hydrochlorothiazide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.