Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Diltiazem is dosed at 0.5–1 mg/kg PO q12-24h in rabbits, per Morissey JM, Carpenter JW. Appendix: Formulary. In: Quesenberry KE, OrcuttCJ, Mans C, et al. Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. | van Zeeland YR.A, Schoemaker NJ. Diagnosis and treatment of cardiovascular disease in small mammals. Proc Conf Annu Assoc Exot Mam Vet; 2018:607-616. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.871 (2026-08-01, PENDING REVIEW). Diltiazem is used in rabbits for Hypertrophic cardiomyopathy; supraventricular and ventricular arrhythmias. Routes documented in rabbits: PO. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Diltiazem in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Cardizem, Dilacor
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 0.5–1 mg/kg | q12-24h | Hypertrophic cardiomyopathy; supraventricular and ventricular arrhythmias | Moderate | Morissey JM, Carpenter JW. Appendix: Formulary. In: Quesenberry KE, OrcuttCJ, Mans C, et al. Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. | van Zeeland YR.A, Schoemaker NJ. Diagnosis and treatment of cardiovascular disease in small mammals. Proc Conf Annu Assoc Exot Mam Vet; 2018:607-616. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.871 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your rabbit's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Blocks L-type calcium channels in cardiac and smooth muscle. Slows AV conduction, reduces heart rate, and reduces myocardial oxygen demand.
Monitor heart rate and blood pressure. Drug of choice for feline hypertrophic cardiomyopathy. Bradycardia, hypotension, AV block possible. Do not combine with beta-blockers without caution.
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Diltiazem dose range in rabbits, with cited source references: PO 0.5–1 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Diltiazem in rabbits: PO.
Diltiazem is indicated in rabbits for: Hypertrophic cardiomyopathy; supraventricular and ventricular arrhythmias.
These are general warnings for Diltiazem across species; consult the rabbit dosing table above for species-specific guidance. Monitor heart rate and blood pressure. Drug of choice for feline hypertrophic cardiomyopathy. Bradycardia, hypotension, AV block possible. Do not combine with beta-blockers without caution.
Why a species-specific page? Diltiazem pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.