Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Spironolactone is dosed at 1–2 mg/kg PO q12h in rabbits, per van Zeeland YR.A, Schoemaker NJ. Diagnosis and treatment of cardiovascular disease in small mammals. Proc Conf Annu Assoc Exot Mam Vet; 2018:607-616. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.872 — Carpenter's Exotic Animal Formulary 6th ed, Table 10.8 (Cardiovascular Agents Used in Rabbits). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Spironolactone is used in rabbits for Diuretic (potassium-sparing). Routes documented in rabbits: PO. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Spironolactone in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Aldactone
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 1–2 mg/kg | q12h | Diuretic (potassium-sparing) | Moderate |
| van Zeeland YR.A, Schoemaker NJ. Diagnosis and treatment of cardiovascular disease in small mammals. Proc Conf Annu Assoc Exot Mam Vet; 2018:607-616. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.872 — Carpenter's Exotic Animal Formulary 6th ed, Table 10.8 (Cardiovascular Agents Used in Rabbits). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 1–2 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 10.8 | 1-2 mg/kg PO q12h |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Competitively blocks aldosterone at mineralocorticoid receptors in the distal nephron. Potassium-sparing diuretic with anti-fibrotic cardiac effects.
Hyperkalemia risk, especially with ACE inhibitors. Monitor electrolytes. Anti-androgenic effects (gynecomastia). Used in CHF as adjunct to furosemide. Give with food.
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Spironolactone dose range in rabbits, with cited source references: PO 1–2 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Spironolactone in rabbits: PO.
Spironolactone is indicated in rabbits for: Diuretic (potassium-sparing).
These are general warnings for Spironolactone across species; consult the rabbit dosing table above for species-specific guidance. Hyperkalemia risk, especially with ACE inhibitors. Monitor electrolytes. Anti-androgenic effects (gynecomastia). Used in CHF as adjunct to furosemide. Give with food.
Why a species-specific page? Spironolactone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.