Cat · Felis catus · typical adult weight 2.50–7.00 kg
Spironolactone is used in cat for Cardiomyopathy adjunct. Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Spironolactone in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Aldactone
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–2 mg/kg | q12h | Long-term | Cardiomyopathy adjunct | Weak | BSAVA Small Animal Formulary, 10th Ed |
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Competitively blocks aldosterone at mineralocorticoid receptors in the distal nephron. Potassium-sparing diuretic with anti-fibrotic cardiac effects.
Hyperkalemia risk, especially with ACE inhibitors. Monitor electrolytes. Anti-androgenic effects (gynecomastia). Used in CHF as adjunct to furosemide. Give with food.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Spironolactone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.