Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Digoxin is dosed at 0.005–0.01 mg/kg PO q12-24h in rabbits, per Morissey JM, Carpenter JW. Appendix: Formulary. In: Quesenberry KE, OrcuttCJ, Mans C, et al. Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.871 (2026-08-01, PENDING REVIEW). Digoxin is used in rabbits for Congestive heart failure; atrial fibrillation. Routes documented in rabbits: PO. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Digoxin in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Lanoxin, Cardoxin
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 0.005–0.01 mg/kg | q12-24h | Congestive heart failure; atrial fibrillation | Weak | Morissey JM, Carpenter JW. Appendix: Formulary. In: Quesenberry KE, OrcuttCJ, Mans C, et al. Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.871 (2026-08-01, PENDING REVIEW) |
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Inhibits Na+/K+-ATPase, increasing intracellular calcium, enhancing contractility (positive inotrope). Also slows AV conduction (vagomimetic).
NARROW therapeutic index. Monitor serum digoxin levels (target 1.0-2.0 ng/ml dogs). Toxicity: arrhythmias, anorexia, vomiting. Reduce dose in renal failure. Many drug interactions (quinidine, verapamil).
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Digoxin dose range in rabbits, with cited source references: PO 0.005–0.01 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Digoxin in rabbits: PO.
Digoxin is indicated in rabbits for: Congestive heart failure; atrial fibrillation.
These are general warnings for Digoxin across species; consult the rabbit dosing table above for species-specific guidance. NARROW therapeutic index. Monitor serum digoxin levels (target 1.0-2.0 ng/ml dogs). Toxicity: arrhythmias, anorexia, vomiting. Reduce dose in renal failure. Many drug interactions (quinidine, verapamil).
Why a species-specific page? Digoxin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.