Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Digoxin is dosed at 0.005–0.01 mg/kg PO q12-24h in guinea pigs, per Ewringmann A, Gloeckner B. Leitsymptome bei Meerschweinchen, Chinchilla und Degu, Enke, Stuttgart, Germany; 2012. / Ewringmann A, Gloeckner B. Leitsymptome bei Hamster, Ratte, Maus und Rennmaus, Enke, Stuttgart, Germany; 2014. / Fehr M, Sassenburg L, Zwart P. Krankheiten der Heimtiere, 8th ed., Schluetersche Verlagsgesellschaft, Hannover, Germany; 2015. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.794 (2026-08-01, PENDING REVIEW) doi:10.1055/b-004-129947. Digoxin is used in guinea pigs for Cardiac (positive inotrope). Routes documented in guinea pigs: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Digoxin in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Lanoxin, Cardoxin
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 0.005–0.01 mg/kg | q12-24h | Cardiac (positive inotrope) | Moderate | Ewringmann A, Gloeckner B. Leitsymptome bei Meerschweinchen, Chinchilla und Degu, Enke, Stuttgart, Germany; 2012. / Ewringmann A, Gloeckner B. Leitsymptome bei Hamster, Ratte, Maus und Rennmaus, Enke, Stuttgart, Germany; 2014. / Fehr M, Sassenburg L, Zwart P. Krankheiten der Heimtiere, 8th ed., Schluetersche Verlagsgesellschaft, Hannover, Germany; 2015. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.794 (2026-08-01, PENDING REVIEW) doi:10.1055/b-004-129947 |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits Na+/K+-ATPase, increasing intracellular calcium, enhancing contractility (positive inotrope). Also slows AV conduction (vagomimetic).
NARROW therapeutic index. Monitor serum digoxin levels (target 1.0-2.0 ng/ml dogs). Toxicity: arrhythmias, anorexia, vomiting. Reduce dose in renal failure. Many drug interactions (quinidine, verapamil).
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Digoxin dose range in guinea pigs, with cited source references: PO 0.005–0.01 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Digoxin in guinea pigs: PO.
Digoxin is indicated in guinea pigs for: Cardiac (positive inotrope).
These are general warnings for Digoxin across species; consult the guinea pig dosing table above for species-specific guidance. NARROW therapeutic index. Monitor serum digoxin levels (target 1.0-2.0 ng/ml dogs). Toxicity: arrhythmias, anorexia, vomiting. Reduce dose in renal failure. Many drug interactions (quinidine, verapamil).
Why a species-specific page? Digoxin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.