Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Pimobendan is dosed at 0.2–0.4 mg/kg PO q12h in guinea pigs, per Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.795 (2026-08-01, PENDING REVIEW). Pimobendan is used in guinea pigs for Heart failure (inodilator). Routes documented in guinea pigs: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Pimobendan in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Vetmedin
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 0.2–0.4 mg/kg | q12h | Heart failure (inodilator) | Moderate | Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.795 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Dual mechanism: inhibits phosphodiesterase III (vasodilation) and sensitizes cardiac troponin C to calcium (positive inotropy without increased oxygen demand).
Give on empty stomach (1 hour before food). Contraindicated in hypertrophic cardiomyopathy (HCM) and aortic stenosis. Monitor for arrhythmias. Standard of care for canine DCM and MMVD (stage B2+).
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Pimobendan dose range in guinea pigs, with cited source references: PO 0.2–0.4 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Pimobendan in guinea pigs: PO.
Pimobendan is indicated in guinea pigs for: Heart failure (inodilator).
These are general warnings for Pimobendan across species; consult the guinea pig dosing table above for species-specific guidance. Give on empty stomach (1 hour before food). Contraindicated in hypertrophic cardiomyopathy (HCM) and aortic stenosis. Monitor for arrhythmias. Standard of care for canine DCM and MMVD (stage B2+).
Why a species-specific page? Pimobendan pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.