Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Phenoxybenzamine is dosed at 0.25 mg/kg PO q12h in guinea pigs, per Mans C. Personal communication; 2016. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.802 (2026-08-01, PENDING REVIEW). Phenoxybenzamine is used in guinea pigs for Urolithiasis (urethral relaxation). Routes documented in guinea pigs: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Phenoxybenzamine in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Dibenzyline
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 0.25 mg/kg | q12h | Urolithiasis (urethral relaxation) | Weak | Mans C. Personal communication; 2016. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.802 (2026-08-01, PENDING REVIEW) |
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Irreversible non-selective alpha-adrenergic blocker. Causes long-lasting vasodilation and reduces urethral smooth muscle tone.
Used for pheochromocytoma, urethral spasm, and functional urethral obstruction. Hypotension common. Effects last 3-4 days after stopping (irreversible binding). Nasal congestion.
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Phenoxybenzamine dose range in guinea pigs, with cited source references: PO 0.25 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Phenoxybenzamine in guinea pigs: PO.
Phenoxybenzamine is indicated in guinea pigs for: Urolithiasis (urethral relaxation).
These are general warnings for Phenoxybenzamine across species; consult the guinea pig dosing table above for species-specific guidance. Used for pheochromocytoma, urethral spasm, and functional urethral obstruction. Hypotension common. Effects last 3-4 days after stopping (irreversible binding). Nasal congestion.
Why a species-specific page? Phenoxybenzamine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.