Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Phenoxybenzamine is dosed at 0.25–1.5 mg/kg PO q12h in dogs, per Volker L. An evaluation of the effectiveness of phenoxybenzamine HCI (Dibenzyline) in horses under field conditions. Internal Smith Kline and French Report;1984. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1039 (2026-08-01).. Phenoxybenzamine is used in dogs for Pheochromocytoma, urethral spasm. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Phenoxybenzamine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Dibenzyline
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.25–1.5 mg/kg | q12h | Variable | Pheochromocytoma, urethral spasm | Moderate | Volker L. An evaluation of the effectiveness of phenoxybenzamine HCI (Dibenzyline) in horses under field conditions. Internal Smith Kline and French Report;1984. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1039 (2026-08-01). |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Irreversible non-selective alpha-adrenergic blocker. Causes long-lasting vasodilation and reduces urethral smooth muscle tone.
Used for pheochromocytoma, urethral spasm, and functional urethral obstruction. Hypotension common. Effects last 3-4 days after stopping (irreversible binding). Nasal congestion.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Phenoxybenzamine dose range in dogs, with cited source references: PO 0.25–1.5 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Phenoxybenzamine in dogs: PO.
Cited course lengths for Phenoxybenzamine in dogs include: Variable. Duration depends on the indication — match it to the specific dose rule in the table above.
Phenoxybenzamine is indicated in dogs for: Pheochromocytoma, urethral spasm.
These are general warnings for Phenoxybenzamine across species; consult the dog dosing table above for species-specific guidance. Used for pheochromocytoma, urethral spasm, and functional urethral obstruction. Hypotension common. Effects last 3-4 days after stopping (irreversible binding). Nasal congestion.
Why a species-specific page? Phenoxybenzamine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.