Phenoxybenzamine for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Phenoxybenzamine is used in dog for Pheochromocytoma, urethral spasm. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Phenoxybenzamine in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Dibenzyline
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.25–1.5 mg/kg | q12h | Variable | Pheochromocytoma, urethral spasm | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Irreversible non-selective alpha-adrenergic blocker. Causes long-lasting vasodilation and reduces urethral smooth muscle tone.
Side effects & warnings
Used for pheochromocytoma, urethral spasm, and functional urethral obstruction. Hypotension common. Effects last 3-4 days after stopping (irreversible binding). Nasal congestion.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Cardiovascular drugs with dog dosing
Phenoxybenzamine dosing in other species
Why a species-specific page? Phenoxybenzamine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.