Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Loperamide is dosed at 0.1 mg/kg PO q8h x3d, then q24h x2d in rabbits, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.878 — Plumb's 10th ed (held) printed p.776, Loperamide monograph spanning p.775-776; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — Carpenter's Exotic Animal Formulary 6th ed, Table 10.10 (Miscellaneous Agents Used in Rabbits). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Loperamide is used in rabbits for Enteropathies (nonspecific diarrhea); reduce gut motility. Routes documented in rabbits: PO. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Loperamide in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Imodium
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 0.1 mg/kg |
| q8h x3d, then q24h x2d |
| Enteropathies (nonspecific diarrhea); reduce gut motility |
| Weak |
| Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.878 — Plumb's 10th ed (held) printed p.776, Loperamide monograph spanning p.775-776; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — Carpenter's Exotic Animal Formulary 6th ed, Table 10.10 (Miscellaneous Agents Used in Rabbits). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.04–0.2 | PO | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.198 | 0.04-0.2 mg/kg p.o. q8-12h |
| 0.1 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 10.10 | 0.1 mg/kg PO q8h × 3 days, then q24h × 2 days |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your rabbit's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mu-opioid receptor agonist in GI tract, slowing motility and increasing segmental contractions. Increases fluid/electrolyte absorption.
CONTRAINDICATED in MDR1-mutant dogs (crosses BBB — severe CNS depression). Avoid in cats. Do not use in infectious diarrhea. May cause constipation, bloating, ileus.
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Loperamide dose range in rabbits, with cited source references: PO 0.1 mg/kg q8h x3d, then q24h x2d. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Loperamide in rabbits: PO.
Loperamide is indicated in rabbits for: Enteropathies (nonspecific diarrhea); reduce gut motility.
These are general warnings for Loperamide across species; consult the rabbit dosing table above for species-specific guidance. CONTRAINDICATED in MDR1-mutant dogs (crosses BBB — severe CNS depression). Avoid in cats. Do not use in infectious diarrhea. May cause constipation, bloating, ileus.
Why a species-specific page? Loperamide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.