Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Loperamide is dosed at 0.1 mg/kg PO q8h in guinea pigs, per Harkness JE. A Practitioner's Guide to Domestic Rodents, American Animal Hospital Association, Lakewood, CO; 1993. / Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.801 (2026-08-01, PENDING REVIEW). Loperamide is used in guinea pigs for Diarrhea. Routes documented in guinea pigs: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Loperamide in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Imodium
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 0.1 mg/kg | q8h | Diarrhea | Moderate | Harkness JE. A Practitioner's Guide to Domestic Rodents, American Animal Hospital Association, Lakewood, CO; 1993. / Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.801 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mu-opioid receptor agonist in GI tract, slowing motility and increasing segmental contractions. Increases fluid/electrolyte absorption.
CONTRAINDICATED in MDR1-mutant dogs (crosses BBB — severe CNS depression). Avoid in cats. Do not use in infectious diarrhea. May cause constipation, bloating, ileus.
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Loperamide dose range in guinea pigs, with cited source references: PO 0.1 mg/kg q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Loperamide in guinea pigs: PO.
Loperamide is indicated in guinea pigs for: Diarrhea.
These are general warnings for Loperamide across species; consult the guinea pig dosing table above for species-specific guidance. CONTRAINDICATED in MDR1-mutant dogs (crosses BBB — severe CNS depression). Avoid in cats. Do not use in infectious diarrhea. May cause constipation, bloating, ileus.
Why a species-specific page? Loperamide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.