Cisapride for Guinea Pig
Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Cisapride is used in guinea pig for GI stasis, Post-anesthetic GI stasis, GI stasis (prokinetic). Routes documented in guinea pig: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 3 cited dose rules for Cisapride in guinea pig, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Propulsid
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–1 mg/kg | q8-12h | As needed | GI stasis | Extrapolated | Carpenter's Exotic Animal Formulary, 6th Ed |
| PO | 0.5–1 mg/kg | q8-12h | Until motility returns | Post-anesthetic GI stasis | Extrapolated | Carpenter's Exotic Animal Formulary, 6th Ed |
| PO | 0.5–1 mg/kg | q8-12h | Until motility restored | GI stasis (prokinetic) | Moderate | Carpenter's Exotic Animal Formulary, 6th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Serotonin 5-HT4 receptor agonist. Enhances acetylcholine release in the myenteric plexus, promoting GI motility throughout the tract.
Side effects & warnings
Withdrawn from human market (cardiac arrhythmias); available as compounded product for veterinary use. Contraindicated with GI obstruction. May interact with azole antifungals.
Species-specific contraindications and adverse-reaction reports for guinea pig may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Gastrointestinal drugs with guinea pig dosing
Cisapride dosing in other species
Why a species-specific page? Cisapride pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pig — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.