Cat · Felis catus · typical adult weight 2.50–7.00 kg
Cisapride is used in cat for Megacolon, constipation, gastroparesis, Post-anesthetic ileus, Megacolon, constipation (prokinetic), Chronic idiopathic constipation. Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 4 cited dose rules for Cisapride in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Propulsid
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.1–1 mg/kg | q8-12h | Chronic as needed | Megacolon, constipation, gastroparesis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 0.25–0.5 mg/kg | q8h | Until motility returns | Post-anesthetic ileus | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 0.1–0.5 mg/kg | q8-12h | Long-term | Megacolon, constipation (prokinetic) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 0.5–1 mg/kg | q8h | Chronic; may lose efficacy over time | Chronic idiopathic constipation | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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Serotonin 5-HT4 receptor agonist. Enhances acetylcholine release in the myenteric plexus, promoting GI motility throughout the tract.
Withdrawn from human market (cardiac arrhythmias); available as compounded product for veterinary use. Contraindicated with GI obstruction. May interact with azole antifungals.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Cisapride pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.