Cat · Felis catus · typical adult weight 2.50–7.00 kg
Cisapride is dosed at 0.1–1 mg/kg PO q8-12h in cats, per Plumb's Veterinary Drug Handbook, 9th Ed. Cisapride is used in cats for Megacolon, constipation, gastroparesis, Post-anesthetic ileus, Megacolon, constipation (prokinetic), Chronic idiopathic constipation. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 4 cited dose rules for Cisapride in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Propulsid
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.1–1 mg/kg | q8-12h | Chronic as needed | Megacolon, constipation, gastroparesis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 0.25–0.5 mg/kg | q8h | Until motility returns | Post-anesthetic ileus |
| Moderate |
| Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 0.1–0.5 mg/kg | q8-12h | Long-term | Megacolon, constipation (prokinetic) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 0.5–1 mg/kg | q8h | Chronic; may lose efficacy over time | Chronic idiopathic constipation | Strong | LeGrange SN, Boothe DM, Herndon S, Willard MD. Pharmacokinetics and suggested oral dosing regimen of cisapride: A study in healthy cats. J Am Anim Hosp Assoc. 1997;33:517-523. doi:10.5326/15473317-33-6-517 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.297 (2026-08-01). |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Serotonin 5-HT4 receptor agonist. Enhances acetylcholine release in the myenteric plexus, promoting GI motility throughout the tract.
Withdrawn from human market (cardiac arrhythmias); available as compounded product for veterinary use. Contraindicated with GI obstruction. May interact with azole antifungals.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cisapride dose ranges in cats, with cited source references: PO 0.1–1 mg/kg q8-12h; PO 0.25–0.5 mg/kg q8h; PO 0.1–0.5 mg/kg q8-12h; PO 0.5–1 mg/kg q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cisapride in cats: PO.
Cited course lengths for Cisapride in cats include: Chronic as needed; Until motility returns; Long-term; Chronic; may lose efficacy over time. Duration depends on the indication — match it to the specific dose rule in the table above.
Cisapride is indicated in cats for: Megacolon, constipation, gastroparesis, Post-anesthetic ileus, Megacolon, constipation (prokinetic), Chronic idiopathic constipation.
These are general warnings for Cisapride across species; consult the cat dosing table above for species-specific guidance. Withdrawn from human market (cardiac arrhythmias); available as compounded product for veterinary use. Contraindicated with GI obstruction. May interact with azole antifungals.
Why a species-specific page? Cisapride pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.