Cat · Felis catus · typical adult weight 2.50–7.00 kg
Denamarin is dosed at 10–20 mg/kg SAMe component PO q24h on empty stomach in cats, per Center S. Update on Canine & Feline Liver Disease. Presented at: ECVIM; 2008. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1166 (2026-08-01).. Denamarin is used in cats for Hepatic support / hepatic lipidosis adjunct. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Denamarin in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Denamarin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10–20 mg/kg SAMe component | q24h on empty stomach | Long-term; minimum 30 days | Hepatic support / hepatic lipidosis adjunct | Moderate | Center S. Update on Canine & Feline Liver Disease. Presented at: ECVIM; 2008. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1166 (2026-08-01). |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Combines S-adenosylmethionine (SAMe) and silybin phosphatidylcholine. SAMe supports glutathione synthesis and hepatocyte repair; silybin provides antioxidant and anti-fibrotic effects.
Give on empty stomach. Generally well tolerated. Mild GI upset possible. Not a substitute for definitive hepatic therapy.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Denamarin dose range in cats, with cited source references: PO 10–20 mg/kg SAMe component q24h on empty stomach. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Denamarin in cats: PO.
Cited course lengths for Denamarin in cats include: Long-term; minimum 30 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Denamarin is indicated in cats for: Hepatic support / hepatic lipidosis adjunct.
These are general warnings for Denamarin across species; consult the cat dosing table above for species-specific guidance. Give on empty stomach. Generally well tolerated. Mild GI upset possible. Not a substitute for definitive hepatic therapy.
Why a species-specific page? Denamarin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.