Cat · Felis catus · typical adult weight 2.50–7.00 kg
Granisetron is dosed at 0.01–0.04 mg/kg IV q12-24h in cats, per Plumb's Veterinary Drug Handbook, 9th Ed. Granisetron is used in cats for Severe nausea/vomiting. Routes documented in cats: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Granisetron in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Kytril, Sancuso
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.01–0.04 mg/kg | q12-24h | Short-term | Severe nausea/vomiting | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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Selective 5-HT3 receptor antagonist that blocks serotonin receptors in the chemoreceptor trigger zone and vagal afferents, suppressing nausea and vomiting.
May cause headache, constipation. QT prolongation reported rarely. Can be used when ondansetron is ineffective.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Granisetron dose range in cats, with cited source references: IV 0.01–0.04 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Granisetron in cats: IV.
Cited course lengths for Granisetron in cats include: Short-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Granisetron is indicated in cats for: Severe nausea/vomiting.
These are general warnings for Granisetron across species; consult the cat dosing table above for species-specific guidance. May cause headache, constipation. QT prolongation reported rarely. Can be used when ondansetron is ineffective.
Why a species-specific page? Granisetron pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.