ExoticRx · exoticrx.com/drugs/granisetron
US brand names:Kytril, Sancuso
Granisetron is dosed at 0.01–0.04 mg/kg IV q12-24h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Selective 5-HT3 receptor antagonist that blocks serotonin receptors in the chemoreceptor trigger zone and vagal afferents, suppressing nausea and vomiting.
May cause headache, constipation. QT prolongation reported rarely. Can be used when ondansetron is ineffective.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.