ExoticRx · exoticrx.com/drugs/aminopentamide
US brand names:Centrine
Aminopentamide is dosed at 0.01–0.03 mg/kg SC q8-12h in dogs, per Instructions for Use: "Dosing guidelines based on manufacturer’s recommendation." (Papich, Aminopentamide monograph, printed p.28) — Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.56 (2026-08-01).. Verify against current literature before clinical use.
Anticholinergic (parasympatholytic) agent that reduces GI smooth muscle spasm by blocking muscarinic acetylcholine receptors in the GI tract, decreasing motility and secretions.
May cause anticholinergic side effects: dry mouth, urinary retention, tachycardia, mydriasis. Contraindicated in GI obstruction and glaucoma. Use cautiously in patients with cardiac disease.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 0.01–0.03 mg/kg | q8-12h | Moderate | Instructions for Use: "Dosing guidelines based on manufacturer’s recommendation." (Papich, Aminopentamide monograph, printed p.28) — Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.56 (2026-08-01). |
| Dog (Domestic) | PO | 0.01–0.03 mg/kg | q8-12h | Moderate | Instructions for Use: "Dosing guidelines based on manufacturer’s recommendation." (Papich, Aminopentamide monograph, printed p.28) — Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.56 (2026-08-01). |
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