ExoticRx · exoticrx.com/drugs/aminopentamide
US brand names:Centrine
Aminopentamide is dosed at 0.01–0.03 mg/kg PO q8-12h in cats, per Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database. Verify against current literature before clinical use.
Anticholinergic (parasympatholytic) agent that reduces GI smooth muscle spasm by blocking muscarinic acetylcholine receptors in the GI tract, decreasing motility and secretions.
May cause anticholinergic side effects: dry mouth, urinary retention, tachycardia, mydriasis. Contraindicated in GI obstruction and glaucoma. Use cautiously in patients with cardiac disease.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | PO | 0.01–0.03 mg/kg | q8-12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
| Dog (Domestic) | SC | 0.01–0.03 mg/kg | q8-12h | Moderate | Instructions for Use: "Dosing guidelines based on manufacturer’s recommendation." (Papich, Aminopentamide monograph, printed p.28) — Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.56 (2026-08-01). |
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