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Aminopentamide

Centrine

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Gastrointestinal

Routes

POIMSC

Indications

diarrheaGI smooth muscle spasmvomiting

Mechanism of Action

Anticholinergic (parasympatholytic) agent that reduces GI smooth muscle spasm by blocking muscarinic acetylcholine receptors in the GI tract, decreasing motility and secretions.

Side effects & warnings

May cause anticholinergic side effects: dry mouth, urinary retention, tachycardia, mydriasis. Contraindicated in GI obstruction and glaucoma. Use cautiously in patients with cardiac disease.

Species with Aminopentamide dosing data (3 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 3 dose rules

Moderate×3

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database

Sample dosing (2 of 3 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)SC0.01–0.03 mg/kgq8-12hModeratePlumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database
Dog (Domestic)PO0.01–0.03 mg/kgq8-12hModeratePlumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database

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