ExoticRx · exoticrx.com/drugs/cisapride
US brand names:Propulsid
Cisapride is dosed at 0.5–2 mg/kg PO q24h in ball pythons, per Carpenter JW, Klaphake E, Gibbons PM, et al. Reptile formulary. In: Divers SJ, Stahl SJ, eds. Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed., Elsevier, St. Louis, MO; 2019:1191-1211. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.272 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.11 (Miscellaneous Agents Used in Reptiles). Located 2026-08-05: the only table covering this species in which the drug's own row prints this dose. The copy held is an ebook conversion with no printed page numbers, so the table is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530. Verify against current literature before clinical use.
Serotonin 5-HT4 receptor agonist. Enhances acetylcholine release in the myenteric plexus, promoting GI motility throughout the tract.
Withdrawn from human market (cardiac arrhythmias); available as compounded product for veterinary use. Contraindicated with GI obstruction. May interact with azole antifungals.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 21 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | PO | 0.5–1 mg/kg | q8h | Strong | LeGrange SN, Boothe DM, Herndon S, Willard MD. Pharmacokinetics and suggested oral dosing regimen of cisapride: A study in healthy cats. J Am Anim Hosp Assoc. 1997;33:517-523. doi:10.5326/15473317-33-6-517 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.297 (2026-08-01). — Plumb's 10th ed (held) printed p.269, Cisapride monograph spanning p.269-270; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Cat (Domestic) | PO | 0.1–1 mg/kg | q8-12h | Strong |
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Species references:All African Grey Parrot drugsAll Ball Python drugsAll Bearded Dragon drugsAll Blue-tongue Skink drugsAll Cat (Domestic) drugsAll Chinchilla drugsAll Corn Snake drugsAll Crested Gecko drugsAll Degu drugsAll Dog (Domestic) drugsAll Dwarf Hamster drugsAll Ferret drugsAll Gerbil drugsAll Guinea Pig drugsAll Mouse drugsAll Pet Rat drugsAll Rabbit (Domestic) drugsAll Red-eared Slider drugsAll Russian Tortoise drugsAll Sugar Glider drugs
| Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.269, Cisapride monograph spanning p.269-270; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |