Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Cisapride is dosed at 0.1–0.5 mg/kg PO q8-12h in dogs, per Whitehead K, Cortes Y, Eirmann L. Gastrointestinal dysmotility disorders in critically ill dogs and cats. J Vet Emerg Crit Car. 2016;26(2):234-253. doi:10.1111/vec.12449 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.297 (2026-08-01).. Cisapride is used in dogs for Gastroparesis, megaesophagus adjunct, Post-operative ileus. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Cisapride in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Propulsid
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.1–0.5 mg/kg | q8-12h | Chronic as needed | Gastroparesis, megaesophagus adjunct | Moderate | Whitehead K, Cortes Y, Eirmann L. Gastrointestinal dysmotility disorders in critically ill dogs and cats. J Vet Emerg Crit Car. 2016;26(2):234-253. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.297 (2026-08-01). |
| PO | 0.1–0.5 mg/kg | q8h | Until motility returns | Post-operative ileus | Moderate | Whitehead K, Cortes Y, Eirmann L. Gastrointestinal dysmotility disorders in critically ill dogs and cats. J Vet Emerg Crit Car. 2016;26(2):234-253. doi:10.1111/vec.12449 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.297 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Serotonin 5-HT4 receptor agonist. Enhances acetylcholine release in the myenteric plexus, promoting GI motility throughout the tract.
Withdrawn from human market (cardiac arrhythmias); available as compounded product for veterinary use. Contraindicated with GI obstruction. May interact with azole antifungals.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cisapride dose ranges in dogs, with cited source references: PO 0.1–0.5 mg/kg q8-12h; PO 0.1–0.5 mg/kg q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cisapride in dogs: PO.
Cited course lengths for Cisapride in dogs include: Chronic as needed; Until motility returns. Duration depends on the indication — match it to the specific dose rule in the table above.
Cisapride is indicated in dogs for: Gastroparesis, megaesophagus adjunct, Post-operative ileus.
These are general warnings for Cisapride across species; consult the dog dosing table above for species-specific guidance. Withdrawn from human market (cardiac arrhythmias); available as compounded product for veterinary use. Contraindicated with GI obstruction. May interact with azole antifungals.
Why a species-specific page? Cisapride pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.