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Cisapride for Dog

Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg

Cisapride is used in dog for Gastroparesis, megaesophagus adjunct, Post-operative ileus. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Cisapride in dog, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Propulsid

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO0.1–0.5 mg/kgq8-12hChronic as neededGastroparesis, megaesophagus adjunctModeratePlumb's Veterinary Drug Handbook, 9th Ed
PO0.1–0.5 mg/kgq8hUntil motility returnsPost-operative ileusModeratePlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Serotonin 5-HT4 receptor agonist. Enhances acetylcholine release in the myenteric plexus, promoting GI motility throughout the tract.

Side effects & warnings

Withdrawn from human market (cardiac arrhythmias); available as compounded product for veterinary use. Contraindicated with GI obstruction. May interact with azole antifungals.

Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Gastrointestinal drugs with dog dosing

Cisapride dosing in other species

Why a species-specific page? Cisapride pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.