Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Cisapride is dosed at 0.1–0.5 mg/kg PO q8-12h in dogs, per Whitehead K, Cortes Y, Eirmann L. Gastrointestinal dysmotility disorders in critically ill dogs and cats. J Vet Emerg Crit Car. 2016;26(2):234-253. doi:10.1111/vec.12449 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.297 (2026-08-01). — Plumb's 10th ed (held) printed p.270, Cisapride monograph spanning p.269-270; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Cisapride is used in dogs for Gastroparesis, megaesophagus adjunct, Post-operative ileus. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Cisapride in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Propulsid
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.1–0.5 mg/kg | q8-12h | Chronic as needed | Gastroparesis, megaesophagus adjunct | Moderate | Whitehead K, Cortes Y, Eirmann L. Gastrointestinal dysmotility disorders in critically ill dogs and cats. J Vet Emerg Crit Car. 2016;26(2):234-253. doi:10.1111/vec.12449 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.297 (2026-08-01). — Plumb's 10th ed (held) printed p.270, Cisapride monograph spanning p.269-270; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| PO | 0.1–0.5 mg/kg | q8h | Until motility returns | Post-operative ileus | Moderate | Whitehead K, Cortes Y, Eirmann L. Gastrointestinal dysmotility disorders in critically ill dogs and cats. J Vet Emerg Crit Car. 2016;26(2):234-253. doi:10.1111/vec.12449 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.297 (2026-08-01). — Plumb's 10th ed (held) printed p.270, Cisapride monograph spanning p.269-270; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.1–0.5 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.104 | 0.1-0.5 mg/kg p.o. q8-12h; some recommend giving 30 minutes before feeding. Some sources state that gra |
| 1 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.104 | me sources state that gradually increasing doses up to 1 mg/kg p.o. q8h may be required (if tolerated) |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Serotonin 5-HT4 receptor agonist. Enhances acetylcholine release in the myenteric plexus, promoting GI motility throughout the tract.
Withdrawn from human market (cardiac arrhythmias); available as compounded product for veterinary use. Contraindicated with GI obstruction. May interact with azole antifungals.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cisapride dose ranges in dogs, with cited source references: PO 0.1–0.5 mg/kg q8-12h; PO 0.1–0.5 mg/kg q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cisapride in dogs: PO.
Cited course lengths for Cisapride in dogs include: Chronic as needed; Until motility returns. Duration depends on the indication — match it to the specific dose rule in the table above.
Cisapride is indicated in dogs for: Gastroparesis, megaesophagus adjunct, Post-operative ileus.
These are general warnings for Cisapride across species; consult the dog dosing table above for species-specific guidance. Withdrawn from human market (cardiac arrhythmias); available as compounded product for veterinary use. Contraindicated with GI obstruction. May interact with azole antifungals.
Why a species-specific page? Cisapride pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.