Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Dirlotapide is used in dog for Obesity management. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Dirlotapide in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Slentrol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.01–0.2 mg/kg | q24h | Up to 12 months; taper over 2-4 weeks when discontinuing | Obesity management | Strong | FDA label (Slentrol); Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selectively inhibits microsomal triglyceride transfer protein in enterocytes, blocking fat absorption and triggering satiety signaling via peptide YY release, reducing appetite and food intake.
Vomiting and diarrhea are common (lipid malabsorption). Elevated liver enzymes possible. Must taper dose gradually when discontinuing. Weight regain occurs after discontinuation. Dogs only.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Dirlotapide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.