Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Isoflurane is dosed at 1.5–3 % (MAC 2.1%) INHALATION Continuous in rabbits, per GillettCS. Selected drug dosages and clinical reference data. In: Manning PJ, Ringler DH, Newcomer CE, eds. The Biology of the Laboratory Rabbit, 2nd ed., Academic Press, San Diego, CA; 1994:467-472. doi:10.1016/b978-0-12-469235-0.50028-2; Harkness JE, Wagner JE. The Biology and Medicine of Rabbits and Rodents, 4th ed., Williams & Wilkins — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.859 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 10.4 (Chemical Restraint/Sedative/Anesthetic/Analgesic Agents Used in Rabbits.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Isoflurane is used in rabbits for General anaesthesia - MAINTENANCE concentration (induction in unpremedicated rabbits requires 3-5%). Routes documented in rabbits: INHALATION. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Isoflurane in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: IsoFlo, Forane
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| INHALATION | 1.5–3 % (MAC 2.1%) | Continuous | Duration of anesthesia | General anaesthesia - MAINTENANCE concentration (induction in unpremedicated rabbits requires 3-5%) | Strong | GillettCS. Selected drug dosages and clinical reference data. In: Manning PJ, Ringler DH, Newcomer CE, eds. The Biology of the Laboratory Rabbit, 2nd ed., Academic Press, San Diego, CA; 1994:467-472. doi:10.1016/b978-0-12-469235-0.50028-2; Harkness JE, Wagner JE. The Biology and Medicine of Rabbits and Rodents, 4th ed., Williams & Wilkins — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.859 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 10.4 (Chemical Restraint/Sedative/Anesthetic/Analgesic Agents Used in Rabbits.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (%) | Route | Source | As printed |
|---|---|---|---|
| 3 | — | Carpenter's Exotic Animal Formulary, 6th edTable 10.4 | 3%-5% induction, 1.5%-1.75% maintenance 3%-5% induction, 2%-3% maintenance |
| 5 | — | Carpenter's Exotic Animal Formulary, 6th edTable 10.4 | 3%-5% induction, 1.5%-1.75% maintenance 3%-5% induction, 2%-3% maintenance |
| 1.5 | — | Carpenter's Exotic Animal Formulary, 6th edTable 10.4 | 3%-5% induction, 1.5%-1.75% maintenance 3%-5% induction, 2%-3% maintenance |
| 1.75 | — | Carpenter's Exotic Animal Formulary, 6th edTable 10.4 | 3%-5% induction, 1.5%-1.75% maintenance 3%-5% induction, 2%-3% maintenance |
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Enhances inhibitory GABA-A receptors and blocks excitatory NMDA receptors, producing dose-dependent general anesthesia.
Most commonly used inhalant anesthetic in veterinary medicine. Dose-dependent hypotension. Minimal hepatic metabolism. Use with precision vaporizer only. Suitable for all species including exotics.
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Isoflurane dose range in rabbits, with cited source references: INHALATION 1.5–3 % (MAC 2.1%) Continuous. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Isoflurane in rabbits: INHALATION.
Cited course lengths for Isoflurane in rabbits include: Duration of anesthesia. Duration depends on the indication — match it to the specific dose rule in the table above.
Isoflurane is indicated in rabbits for: General anaesthesia - MAINTENANCE concentration (induction in unpremedicated rabbits requires 3-5%).
These are general warnings for Isoflurane across species; consult the rabbit dosing table above for species-specific guidance. Most commonly used inhalant anesthetic in veterinary medicine. Dose-dependent hypotension. Minimal hepatic metabolism. Use with precision vaporizer only. Suitable for all species including exotics.
Why a species-specific page? Isoflurane pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 2 |
| — |
| Carpenter's Exotic Animal Formulary, 6th edTable 10.4 |
| 3%-5% induction, 1.5%-1.75% maintenance 3%-5% induction, 2%-3% maintenance |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.