Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Isoflurane is dosed at 1.5–3 % (MAC 2.1%) INHALATION Continuous in rabbits, per GillettCS. Selected drug dosages and clinical reference data. In: Manning PJ, Ringler DH, Newcomer CE, eds. The Biology of the Laboratory Rabbit, 2nd ed., Academic Press, San Diego, CA; 1994:467-472. doi:10.1016/b978-0-12-469235-0.50028-2; Harkness JE, Wagner JE. The Biology and Medicine of Rabbits and Rodents, 4th ed., Williams & Wilkins — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.859 (2026-08-01).. Isoflurane is used in rabbits for General anesthesia. Routes documented in rabbits: INHALATION. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Isoflurane in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: IsoFlo, Forane
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| INHALATION | 1.5–3 % (MAC 2.1%) | Continuous | Duration of anesthesia | General anesthesia |
| GillettCS. Selected drug dosages and clinical reference data. In: Manning PJ, Ringler DH, Newcomer CE, eds. The Biology of the Laboratory Rabbit, 2nd ed., Academic Press, San Diego, CA; 1994:467-472. doi:10.1016/b978-0-12-469235-0.50028-2; Harkness JE, Wagner JE. The Biology and Medicine of Rabbits and Rodents, 4th ed., Williams & Wilkins — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.859 (2026-08-01). |
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Enhances inhibitory GABA-A receptors and blocks excitatory NMDA receptors, producing dose-dependent general anesthesia.
Most commonly used inhalant anesthetic in veterinary medicine. Dose-dependent hypotension. Minimal hepatic metabolism. Use with precision vaporizer only. Suitable for all species including exotics.
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Isoflurane dose range in rabbits, with cited source references: INHALATION 1.5–3 % (MAC 2.1%) Continuous. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Isoflurane in rabbits: INHALATION.
Cited course lengths for Isoflurane in rabbits include: Duration of anesthesia. Duration depends on the indication — match it to the specific dose rule in the table above.
Isoflurane is indicated in rabbits for: General anesthesia.
These are general warnings for Isoflurane across species; consult the rabbit dosing table above for species-specific guidance. Most commonly used inhalant anesthetic in veterinary medicine. Dose-dependent hypotension. Minimal hepatic metabolism. Use with precision vaporizer only. Suitable for all species including exotics.
Why a species-specific page? Isoflurane pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.