Cat · Felis catus · typical adult weight 2.50–7.00 kg
Isoflurane is dosed at 1.5–2.5 % (MAC 1.6%) INHALATION Continuous in cats, per Shaughnessy MR, Hofmeister EH. A systematic review of sevoflurane and isoflurane minimum alveolar concentration in domestic cats. Vet Anaesth Analg. 2014;41(1):1-13. doi:10.1111/vaa.12083 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.724 (2026-08-01).. Isoflurane is used in cats for General anesthesia (maintenance). Routes documented in cats: INHALATION. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Isoflurane in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: IsoFlo, Forane
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| INHALATION | 1.5–2.5 % (MAC 1.6%) | Continuous | Duration of anesthesia | General anesthesia (maintenance) | Strong | Shaughnessy MR, Hofmeister EH. A systematic review of sevoflurane and isoflurane minimum alveolar concentration in domestic cats. Vet Anaesth Analg. 2014;41(1):1-13. doi:10.1111/vaa.12083 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.724 (2026-08-01). |
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Enhances inhibitory GABA-A receptors and blocks excitatory NMDA receptors, producing dose-dependent general anesthesia.
Most commonly used inhalant anesthetic in veterinary medicine. Dose-dependent hypotension. Minimal hepatic metabolism. Use with precision vaporizer only. Suitable for all species including exotics.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Isoflurane dose range in cats, with cited source references: INHALATION 1.5–2.5 % (MAC 1.6%) Continuous. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Isoflurane in cats: INHALATION.
Cited course lengths for Isoflurane in cats include: Duration of anesthesia. Duration depends on the indication — match it to the specific dose rule in the table above.
Isoflurane is indicated in cats for: General anesthesia (maintenance).
These are general warnings for Isoflurane across species; consult the cat dosing table above for species-specific guidance. Most commonly used inhalant anesthetic in veterinary medicine. Dose-dependent hypotension. Minimal hepatic metabolism. Use with precision vaporizer only. Suitable for all species including exotics.
Why a species-specific page? Isoflurane pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.