Cat · Felis catus · typical adult weight 2.50–7.00 kg
Propofol is dosed at 4–8 mg/kg IV To effect (titrate IV) in cats, per Papich MG. Saunders Handbook of Veterinary Drugs, Propofol, Small Animal Dosage, Cats, printed p.685 (corpus PDF p.713) - "Anesthesia induction: 4-8 mg/kg IV slowly." NOTE - the previously cited Plumb's 10th ed printed p.1084 prints 2-8 mg/kg extra-label to effect and 8-13.2 mg/kg label unpremedicated, and does not carry the 4 bound. Served 4-8 lies wholly inside plumb's 2-8, so this is a locator fix and no dose changes. The rule's Oliveira 2018 primary citation reports a study ARM (5.3 +/- 1.1 mg/kg), not a recommendation.. Propofol is used in cats for Induction of general anesthesia. Routes documented in cats: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Propofol in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rapinovet, PropoFlo
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 4–8 mg/kg | To effect (titrate IV) | Single induction | Induction of general anesthesia | Strong | Papich MG. Saunders Handbook of Veterinary Drugs, Propofol, Small Animal Dosage, Cats, printed p.685 (corpus PDF p.713) - "Anesthesia induction: 4-8 mg/kg IV slowly." NOTE - the previously cited Plumb's 10th ed printed p.1084 prints 2-8 mg/kg extra-label to effect and 8-13.2 mg/kg label unpremedicated, and does not carry the 4 bound. Served 4-8 lies wholly inside plumb's 2-8, so this is a locator fix and no dose changes. The rule's Oliveira 2018 primary citation reports a study ARM (5.3 +/- 1.1 mg/kg), not a recommendation. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (%) | Route | Source | As printed |
|---|---|---|---|
| 24 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | sedatives are used, reduce by 16%-24%. If combined with midazolam, the propo- |
| 16 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | sedatives are used, reduce by 16%-24%. If combined with midazolam, the propo- |
| 25 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | fol requirement listed can be reduced by as much as 25%. |
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Enhances GABA-A receptor activity, producing rapid-onset, ultra-short-acting general anesthesia. Also has some NMDA receptor antagonism.
Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Propofol dose range in cats, with cited source references: IV 4–8 mg/kg To effect (titrate IV). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Propofol in cats: IV.
Cited course lengths for Propofol in cats include: Single induction. Duration depends on the indication — match it to the specific dose rule in the table above.
Propofol is indicated in cats for: Induction of general anesthesia.
These are general warnings for Propofol across species; consult the cat dosing table above for species-specific guidance. Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Why a species-specific page? Propofol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| Dose (mcg/kg) | Route | Source | As printed |
|---|
| 200–300 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | • CRI: 6 mg/kg slowly IV, followed by 200-300 mcg/kg/min (0.2-0.3 mg/kg) IV. |
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 8 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.363 | 8 mg/kg i.v.; premedicated 2-5 mg/kg i.v. 348 BSAVA Small Animal Formulary 10th edition: Part |
| 2–5 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.363 | 8 mg/kg i.v.; premedicated 2-5 mg/kg i.v. 348 BSAVA Small Animal Formulary 10th edition: Part A - Canine and Feline |
| 15 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | For short-term procedures the total dose is 15 mg/kg for 30-minute protocol. |
| 10 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | • Short-term surgery: 10 mg/kg IV dose delivered over 1 minute (duration of |
| 0.2–0.3 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | • CRI: 6 mg/kg slowly IV, followed by 200-300 mcg/kg/min (0.2-0.3 mg/kg) IV. |
| 6 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | • CRI: 6 mg/kg slowly IV, followed by 200-300 mcg/kg/min (0.2-0.3 mg/kg) IV. |
| 1–3 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | of 1-3 mg/kg IV can be administered as needed. If other preanesthetics and |
| 4–8 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.713 | • Anesthesia induction: 4-8 mg/kg IV slowly. After initial dose, incremental doses |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.