Reptile · Tiliqua scincoides · typical adult weight 0.25–0.60 kg
Propofol is dosed at 10 mg/kg IV, IO once (induction) in blue-tongue skinks, per BennettRA, Schumacher J, Hedjazi-Haring K, et al. Cardiopulmonary and anesthetic effects of propofol administered intraosseously to green iguanas. J Am Vet Med Assoc. 1998;212:93-98. | Divers SJ, Stahl SJ. Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed., Elsevier, St. Louis, MO; 2019. | Nardini G, Di Girolamo N, Leopardi S, et al. Evaluation of liver parenchyma and perfusion using dynamic contrast-enhanced computed tomography and contrast-enhanced ultrasonography in captive green iguanas (Iguana iguana) under general anesthesia. BMC Vet Res. 2014;10:112-120. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.248 doi:10.2460/javma.1998.212.01.93 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.5 (Chemical Restraint/Anesthetic Agents Used in Reptiles.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530. Propofol is used in blue-tongue skinks for Anaesthetic induction. Routes documented in blue-tongue skinks: IV, IO. A typical adult blue-tongue skink weighs 0.25–0.60 kg. ExoticRx lists 1 cited dose rule for Propofol in blue-tongue skinks, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rapinovet, PropoFlo
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IV, IO | 10 mg/kg | once (induction) | Anaesthetic induction | Moderate | BennettRA, Schumacher J, Hedjazi-Haring K, et al. Cardiopulmonary and anesthetic effects of propofol administered intraosseously to green iguanas. J Am Vet Med Assoc. 1998;212:93-98. | Divers SJ, Stahl SJ. Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed., Elsevier, St. Louis, MO; 2019. | Nardini G, Di Girolamo N, Leopardi S, et al. Evaluation of liver parenchyma and perfusion using dynamic contrast-enhanced computed tomography and contrast-enhanced ultrasonography in captive green iguanas (Iguana iguana) under general anesthesia. BMC Vet Res. 2014;10:112-120. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.248 doi:10.2460/javma.1998.212.01.93 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.5 (Chemical Restraint/Anesthetic Agents Used in Reptiles.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 5–10 | IV | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.269 | 5-10 mg/kg i.v., intraosseous |
| 10 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 10 mg/kg IV, IO,108,342 |
| 10–15 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 10-15 mg/kg IV |
| 0.5–1 | IV | Carpenter's Exotic Animal Formulary, 6th ed |
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These ranges are per kg. Enter your blue-tongue skink's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Enhances GABA-A receptor activity, producing rapid-onset, ultra-short-acting general anesthesia. Also has some NMDA receptor antagonism.
Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Species-specific contraindications and adverse-reaction reports for blue-tongue skinks may differ from canine / feline reference data — consult the primary citations listed with each rule.
Propofol dose range in blue-tongue skinks, with cited source references: IV, IO 10 mg/kg once (induction). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Propofol in blue-tongue skinks: IV, IO.
Propofol is indicated in blue-tongue skinks for: Anaesthetic induction.
These are general warnings for Propofol across species; consult the blue-tongue skink dosing table above for species-specific guidance. Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Why a species-specific page? Propofol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in blue-tongue skinks — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 0.3-0.5 mg/kg/min IV, IO constant rate infusion, or 0.5-1 mg/kg IV, IO periodic bolus |
| 0.3–0.5 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 0.3-0.5 mg/kg/min IV, IO constant rate infusion, or 0.5-1 mg/kg IV, IO periodic bolus |
| 35 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.4 | 35 mg/kg ICe32 Deep anesthesia in 83% of tiger salamanders32 |
| 60–100 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.4 | 60-100 mg/kg ICe52 Euthanasia |
| 0.3–0.5 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 0.3-0.5 mg/kg/min IV, IO constant rate infusion, or 0.5-1 mg/kg IV, IO periodic bolus298 Most species/maintenance anesthesia; must provide respiratory and thermal support |
| 0.5–1 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 0.3-0.5 mg/kg/min IV, IO constant rate infusion, or 0.5-1 mg/kg IV, IO periodic bolus298 Most species/maintenance anesthesia; must provide respiratory and thermal support |
| 10 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 10 mg/kg IV, IO24,71,242 Lizards, snakes/0.25 mg/kg/min may be given for maintenance;99 green iguanas/anesthetic induction242 |
| 10–15 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 10-15 mg/kg IV187 Crocodilians/duration, 0.5-1.5 hr; maintain on gas anesthetics; experimental IM with hyaluronidase |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.