Reptile · Eublepharis macularius · typical adult weight 0.04–0.10 kg
Propofol is dosed at 10 mg/kg IV, IO induction dose; 0.25 mg/kg/min for maintenance in leopard geckos, per 24. Bennett RA, Schumacher J, Hedjazi-Haring K, et al. Cardiopulmonary and anesthetic effects of propofol administered intraosseously to green iguanas. J Am Vet Med Assoc. 1998;212:93-98. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1412 (2026-08-01, PENDING REVIEW). Propofol is used in leopard geckos for Anaesthetic induction. Routes documented in leopard geckos: IV, IO. A typical adult leopard gecko weighs 0.04–0.10 kg. ExoticRx lists 1 cited dose rule for Propofol in leopard geckos, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rapinovet, PropoFlo
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IV, IO | 10 mg/kg | induction dose; 0.25 mg/kg/min for maintenance | Anaesthetic induction | Weak | 24. Bennett RA, Schumacher J, Hedjazi-Haring K, et al. Cardiopulmonary and anesthetic effects of propofol administered intraosseously to green iguanas. J Am Vet Med Assoc. 1998;212:93-98. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1412 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your leopard gecko's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Enhances GABA-A receptor activity, producing rapid-onset, ultra-short-acting general anesthesia. Also has some NMDA receptor antagonism.
Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Species-specific contraindications and adverse-reaction reports for leopard geckos may differ from canine / feline reference data — consult the primary citations listed with each rule.
Propofol dose range in leopard geckos, with cited source references: IV, IO 10 mg/kg induction dose; 0.25 mg/kg/min for maintenance. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Propofol in leopard geckos: IV, IO.
Propofol is indicated in leopard geckos for: Anaesthetic induction.
These are general warnings for Propofol across species; consult the leopard gecko dosing table above for species-specific guidance. Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Why a species-specific page? Propofol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in leopard geckos — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.