Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Propofol is dosed at 12–15 mg/kg IV single induction dose in eastern box turtles, per 68. Divers SJ. The use of propofol in reptile anesthesia. Proc Annu Conf Assoc Rept Amph Vet. 1996;57-59. | 318. Stahl S, Donoghue S. Pharyngostomy tube placement, management and use for nutritional support in chelonian patients. Proc Annu Conf Assoc Rept Amph Vet. 1997;93-97. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1412 — SOURCE EDITION: Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530. Propofol is used in eastern box turtles for anaesthetic induction. Routes documented in eastern box turtles: IV. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 1 cited dose rule for Propofol in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rapinovet, PropoFlo
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IV | 12–15 mg/kg | single induction dose | anaesthetic induction | Weak | 68. Divers SJ. The use of propofol in reptile anesthesia. Proc Annu Conf Assoc Rept Amph Vet. 1996;57-59. | 318. Stahl S, Donoghue S. Pharyngostomy tube placement, management and use for nutritional support in chelonian patients. Proc Annu Conf Assoc Rept Amph Vet. 1997;93-97. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1412 — SOURCE EDITION: Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 5–10 | IV | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.269 | 5-10 mg/kg i.v., intraosseous |
| 5 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 5 mg/kg IV |
| 10 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 10 mg/kg IV (supravertebral sinus)502 |
| 12–15 | IV | Carpenter's Exotic Animal Formulary, 6th ed |
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These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Enhances GABA-A receptor activity, producing rapid-onset, ultra-short-acting general anesthesia. Also has some NMDA receptor antagonism.
Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Propofol dose range in eastern box turtles, with cited source references: IV 12–15 mg/kg single induction dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Propofol in eastern box turtles: IV.
Propofol is indicated in eastern box turtles for: anaesthetic induction.
These are general warnings for Propofol across species; consult the eastern box turtle dosing table above for species-specific guidance. Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Why a species-specific page? Propofol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 12-15 mg/kg IV,446 |
| 20 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 20 mg/kg IV (supravertebral sinus)502 |
| 10–15 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 10-15 mg/kg IV |
| 0.5–1 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 0.3-0.5 mg/kg/min IV, IO constant rate infusion, or 0.5-1 mg/kg IV, IO periodic bolus |
| 3–5 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 3-5 mg/kg IV supravertebral sinus |
| 0.3–0.5 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 0.3-0.5 mg/kg/min IV, IO constant rate infusion, or 0.5-1 mg/kg IV, IO periodic bolus |
| 35 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.4 | 35 mg/kg ICe32 Deep anesthesia in 83% of tiger salamanders32 |
| 60–100 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.4 | 60-100 mg/kg ICe52 Euthanasia |
| 0.3–0.5 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 0.3-0.5 mg/kg/min IV, IO constant rate infusion, or 0.5-1 mg/kg IV, IO periodic bolus298 Most species/maintenance anesthesia; must provide respiratory and thermal support |
| 0.5–1 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 0.3-0.5 mg/kg/min IV, IO constant rate infusion, or 0.5-1 mg/kg IV, IO periodic bolus298 Most species/maintenance anesthesia; must provide respiratory and thermal support |
| 3–5 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 3-5 mg/kg IV supravertebral sinus81 Chelonians/sedation (i.e., shell repair) |
| 5 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 5 mg/kg IV106 Snapping turtles/anesthetic induction |
| 10 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 10 mg/kg IV (supravertebral sinus)350 Red-eared sliders/40-85 min anesthesia |
| 12–15 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 12-15 mg/kg IV68,318 Chelonians/lower dosages (5-10 mg/kg IV295) may be used; 1 mg/kg/min may be given for maintenance295 |
| 20 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 20 mg/kg IV (supravertebral sinus)350 Red-eared sliders/60-120 min anesthesia |
| 10–15 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 10-15 mg/kg IV187 Crocodilians/duration, 0.5-1.5 hr; maintain on gas anesthetics; experimental IM with hyaluronidase |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.