ExoticRx · exoticrx.com/drugs/propofol
US brand names:Rapinovet, PropoFlo
Propofol is dosed at 5–10 mg/kg IV To effect in african grey parrots, per Carpenter's Exotic Animal Formulary, 6th Ed. Verify against current literature before clinical use.
Enhances GABA-A receptor activity, producing rapid-onset, ultra-short-acting general anesthesia. Also has some NMDA receptor antagonism.
Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Species references:All African Grey Parrot drugsAll Cat (Domestic) drugsAll Dog (Domestic) drugsAll Horse (Equine) drugsAll Rabbit (Domestic) drugsAll Swine (Pig) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 6 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 4–6 mg/kg | To effect (titrate IV) | Strong | Propoflo - Propofol Injection, Emulsion [US Product Label for Dogs]. Zoetis Inc.; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9c7679bd-31d1-4a62-b7b5-d0c52be1fccd — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1111 (2026-08-01). |
| Cat (Domestic) | IV | 4–8 mg/kg | To effect (titrate IV) | Strong | Oliveira RLS, Moreira CMR, Barcellos MCB, Silva CPP, Teixeira JGC, Souza HJM. Effect of administration rate on propofol requirement in cats. J Feline Med Surg. 2018;20(2):91-94. doi:10.1177/1098612x17695891 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1111 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.