ExoticRx · exoticrx.com/drugs/desflurane
US brand names:Suprane
Volatile halogenated ether. Enhances inhibitory neurotransmission (GABA, glycine) and inhibits excitatory channels (NMDA, nAChR). Very low blood:gas solubility (0.42).
Requires heated vaporizer (near boiling point at room temperature). Pungent — causes airway irritation, not suitable for mask induction. Fastest recovery of all inhalants. Expensive.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | INHALATION | Higher MAC in cats | Continuous vaporizer delivery | Strong | Grubb T. Gas anesthetics: Where are we now? Presented at: Proceedings: IVECCS; 2004. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.377 (2026-08-01). |
| Dog (Domestic) | INHALATION | Fastest recovery of inhalants | Continuous vaporizer delivery | Strong | Grubb T. Gas anesthetics: Where are we now? Presented at: Proceedings: IVECCS; 2004. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.377 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.