ExoticRx · exoticrx.com/drugs/dexmedetomidine
Dexdomitor, Sileo
Selective alpha-2 adrenergic agonist. Produces dose-dependent sedation, analgesia, and muscle relaxation via CNS depression.
Profound cardiovascular effects: initial hypertension then hypotension, bradycardia. Avoid in animals with cardiac disease, hepatic or renal disease. Reversible with atipamezole. Vomiting common after IM injection.
Species references:All African Grey Parrot drugsAll Ball Python drugsAll Bearded Dragon drugsAll Cat (Domestic) drugsAll Dog (Domestic) drugsAll Guinea Pig drugsAll Rabbit (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Dexmedetomidine CRI dose rule from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.
| Species | Route | Rate | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.0005–0.002 mg/kgper hour (CRI) | CRI for sedation/analgesia | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
CRI for sedation/analgesia
A dog/cat sample is shown here. Cited dosing for all 7 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.