Desflurane for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Desflurane is used in dog for Maintenance of general anesthesia. Routes documented in dog: INHALATION. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Desflurane in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Suprane
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| INHALATION | 0 MAC 7.2% (dog) | Continuous vaporizer delivery | Duration of procedure | Maintenance of general anesthesia | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Volatile halogenated ether. Enhances inhibitory neurotransmission (GABA, glycine) and inhibits excitatory channels (NMDA, nAChR). Very low blood:gas solubility (0.42).
Side effects & warnings
Requires heated vaporizer (near boiling point at room temperature). Pungent — causes airway irritation, not suitable for mask induction. Fastest recovery of all inhalants. Expensive.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Anesthetic drugs with dog dosing
Desflurane dosing in other species
Why a species-specific page? Desflurane pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.