Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Tiletamine-Zolazepam is dosed at 6.6–13.2 mg/kg IM Single dose (may supplement) in dogs, per TELAZOL - Tiletamine Hydrochloride and Zolazepam Hydrochloride Injection, Powder, for Solution [US Product Label for Dogs and Cats]. Zoetis Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3ef51363-2236-40aa-bf32-601c9f1c722a — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1265 (2026-08-01).. Tiletamine-Zolazepam is used in dogs for Short procedures, immobilization. Routes documented in dogs: IM. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Tiletamine-Zolazepam in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Telazol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 6.6–13.2 mg/kg | Single dose (may supplement) | 20-40 min procedure time | Short procedures, immobilization | Strong | TELAZOL - Tiletamine Hydrochloride and Zolazepam Hydrochloride Injection, Powder, for Solution [US Product Label for Dogs and Cats]. Zoetis Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3ef51363-2236-40aa-bf32-601c9f1c722a — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1265 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Tiletamine is a dissociative NMDA antagonist providing anesthesia; zolazepam is a benzodiazepine providing muscle relaxation and reducing emergence reactions.
Controlled substance (CIII). Prolonged recovery in cats (zolazepam component). Causes pain at IM injection site. Cannot titrate once given IM. Avoid in renal/hepatic disease.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tiletamine-Zolazepam dose range in dogs, with cited source references: IM 6.6–13.2 mg/kg Single dose (may supplement). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tiletamine-Zolazepam in dogs: IM.
Cited course lengths for Tiletamine-Zolazepam in dogs include: 20-40 min procedure time. Duration depends on the indication — match it to the specific dose rule in the table above.
Tiletamine-Zolazepam is indicated in dogs for: Short procedures, immobilization.
These are general warnings for Tiletamine-Zolazepam across species; consult the dog dosing table above for species-specific guidance. Controlled substance (CIII). Prolonged recovery in cats (zolazepam component). Causes pain at IM injection site. Cannot titrate once given IM. Avoid in renal/hepatic disease.
Why a species-specific page? Tiletamine-Zolazepam pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.