Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Propofol is dosed at 4–6 mg/kg IV To effect (titrate IV) in dogs, per Propoflo - Propofol Injection, Emulsion [US Product Label for Dogs]. Zoetis Inc.; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9c7679bd-31d1-4a62-b7b5-d0c52be1fccd — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1111 (2026-08-01).. Propofol is used in dogs for Induction of general anesthesia. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Propofol in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rapinovet, PropoFlo
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 4–6 mg/kg | To effect (titrate IV) | Single induction | Induction of general anesthesia | Strong | Propoflo - Propofol Injection, Emulsion [US Product Label for Dogs]. Zoetis Inc.; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9c7679bd-31d1-4a62-b7b5-d0c52be1fccd — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1111 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Enhances GABA-A receptor activity, producing rapid-onset, ultra-short-acting general anesthesia. Also has some NMDA receptor antagonism.
Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Propofol dose range in dogs, with cited source references: IV 4–6 mg/kg To effect (titrate IV). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Propofol in dogs: IV.
Cited course lengths for Propofol in dogs include: Single induction. Duration depends on the indication — match it to the specific dose rule in the table above.
Propofol is indicated in dogs for: Induction of general anesthesia.
These are general warnings for Propofol across species; consult the dog dosing table above for species-specific guidance. Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Why a species-specific page? Propofol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.