Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Propofol is dosed at 6–10 mg/kg IV To effect in rabbits, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) ed. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.864 (2026-08-01). — Plumb's 10th ed (held) printed p.1080, Propofol monograph spanning p.1080-1085; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — Carpenter's Exotic Animal Formulary 6th ed, Table 10.4 (Chemical Restraint/Sedative/Anesthetic/Analgesic Agents Used in Rabbits.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Propofol is used in rabbits for Induction of general anesthesia. Routes documented in rabbits: IV. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Propofol in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rapinovet, PropoFlo
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 6–10 mg/kg | To effect | Single induction | Induction of general anesthesia | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) ed. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.864 (2026-08-01). — Plumb's 10th ed (held) printed p.1080, Propofol monograph spanning p.1080-1085; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — Carpenter's Exotic Animal Formulary 6th ed, Table 10.4 (Chemical Restraint/Sedative/Anesthetic/Analgesic Agents Used in Rabbits.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 7.5–15 | IV | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.269 | unpremedicated 7.5-15 mg/kg i.v.; premedicated 2-6 mg/kg i.v. |
| 2–6 | IV | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.269 | unpremedicated 7.5-15 mg/kg i.v.; premedicated 2-6 mg/kg i.v. |
| 6–8 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 10.4 | 6-8 mg/kg IV induction, followed by 0.8-1 mg/kg/min CRI |
| 0.8–1 |
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Enhances GABA-A receptor activity, producing rapid-onset, ultra-short-acting general anesthesia. Also has some NMDA receptor antagonism.
Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Propofol dose range in rabbits, with cited source references: IV 6–10 mg/kg To effect. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Propofol in rabbits: IV.
Cited course lengths for Propofol in rabbits include: Single induction. Duration depends on the indication — match it to the specific dose rule in the table above.
Propofol is indicated in rabbits for: Induction of general anesthesia.
These are general warnings for Propofol across species; consult the rabbit dosing table above for species-specific guidance. Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Why a species-specific page? Propofol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| IV |
| Carpenter's Exotic Animal Formulary, 6th edTable 10.4 |
| 6-8 mg/kg IV induction, followed by 0.8-1 mg/kg/min CRI |
| 7.5–15 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 10.4 | 7.5-15 mg/kg IV |
| 5–14 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 10.4 | 5-14 mg/kg slow IV to effect or 20 mg/kg/min CRI |
| 1 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 10.4 | 12.5 mg/kg IV, IO followed by 1 mg/kg/min CRI |
| 5 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 10.4 | 16 ± 5 mg/kg IV |
| 12.5 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 10.4 | 12.5 mg/kg IV, IO followed by 1 mg/kg/min CRI |
| 20 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 10.4 | 5-14 mg/kg slow IV to effect or 20 mg/kg/min CRI |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.