Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Propofol is dosed at 2–3 mg/kg IV to effect in horses, per Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed. (2016), Propofol, printed p.686 (corpus PDF p.714) for 2 mg/kg IV; and Guaifenesin, printed p.371 (corpus PDF p.399) for 3 mg/kg IV — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Propofol is used in horses for Short-term anesthesia induction/maintenance. Routes documented in horses: IV. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 1 cited dose rule for Propofol in horses, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rapinovet, PropoFlo
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IV | 2–3 mg/kg | to effect | Short-term anesthesia induction/maintenance | Weak | Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed. (2016), Propofol, printed p.686 (corpus PDF p.714) for 2 mg/kg IV; and Guaifenesin, printed p.371 (corpus PDF p.399) for 3 mg/kg IV — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 2 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.714 | • 2 mg/kg IV bolus. Guaifenesin (90 mg/kg IV) should be administered prior to |
| 90 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.714 | • 2 mg/kg IV bolus. Guaifenesin (90 mg/kg IV) should be administered prior to |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Enhances GABA-A receptor activity, producing rapid-onset, ultra-short-acting general anesthesia. Also has some NMDA receptor antagonism.
Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Propofol dose range in horses, with cited source references: IV 2–3 mg/kg to effect. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Propofol in horses: IV.
Propofol is indicated in horses for: Short-term anesthesia induction/maintenance.
These are general warnings for Propofol across species; consult the horse dosing table above for species-specific guidance. Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Why a species-specific page? Propofol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.