Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Propofol is dosed at 2–3 mg/kg IV to effect in horses, per Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed. (2016), Propofol, printed p.686 (corpus PDF p.714) for 2 mg/kg IV; and Guaifenesin, printed p.371 (corpus PDF p.399) for 3 mg/kg IV. Propofol is used in horses for Short-term anesthesia induction/maintenance. Routes documented in horses: IV. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 1 cited dose rule for Propofol in horses, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rapinovet, PropoFlo
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IV | 2–3 mg/kg | to effect | Short-term anesthesia induction/maintenance | Moderate | Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed. (2016), Propofol, printed p.686 (corpus PDF p.714) for 2 mg/kg IV; and Guaifenesin, printed p.371 (corpus PDF p.399) for 3 mg/kg IV |
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Enhances GABA-A receptor activity, producing rapid-onset, ultra-short-acting general anesthesia. Also has some NMDA receptor antagonism.
Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Propofol dose range in horses, with cited source references: IV 2–3 mg/kg to effect. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Propofol in horses: IV.
Propofol is indicated in horses for: Short-term anesthesia induction/maintenance.
These are general warnings for Propofol across species; consult the horse dosing table above for species-specific guidance. Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Why a species-specific page? Propofol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.