Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Nitrous Oxide is used in dog for Anesthetic adjunct (MAC reduction). Routes documented in dog: INHALATION. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Nitrous Oxide in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: N2O
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| INHALATION | 0 % inspired | Continuous during anesthesia | Duration of procedure; 100% O2 for 5 min after | Anesthetic adjunct (MAC reduction) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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NMDA receptor antagonist with analgesic and anxiolytic properties. Low potency (MAC >100%) so used as adjunct to reduce requirements of other inhalants.
Second gas effect. Diffusion hypoxia during recovery — give 100% O2 for 5 min after discontinuation. Contraindicated with pneumothorax/GDV (gas-filled spaces expand). Expands air-filled viscera.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Nitrous Oxide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.