ExoticRx · exoticrx.com/drugs/tiletamine-zolazepam
US brand names:Telazol
Tiletamine-Zolazepam is dosed at 9.7–15.8 mg/kg IM Single dose in cats, per TELAZOL - Tiletamine Hydrochloride and Zolazepam Hydrochloride Injection, Powder, for Solution [US Product Label for Dogs and Cats]. Zoetis Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3ef51363-2236-40aa-bf32-601c9f1c722a — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1265 (2026-08-01).. Verify against current literature before clinical use.
Tiletamine is a dissociative NMDA antagonist providing anesthesia; zolazepam is a benzodiazepine providing muscle relaxation and reducing emergence reactions.
Controlled substance (CIII). Prolonged recovery in cats (zolazepam component). Causes pain at IM injection site. Cannot titrate once given IM. Avoid in renal/hepatic disease.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Controlled substance in the US
Controlled-drug status and schedules differ by country — check your local scheduling rules.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | IM | 9.7–15.8 mg/kg | Single dose | Strong | TELAZOL - Tiletamine Hydrochloride and Zolazepam Hydrochloride Injection, Powder, for Solution [US Product Label for Dogs and Cats]. Zoetis Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3ef51363-2236-40aa-bf32-601c9f1c722a — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1265 (2026-08-01). |
| Dog (Domestic) | IM | 6.6–13.2 mg/kg | Single dose (may supplement) | Strong | TELAZOL - Tiletamine Hydrochloride and Zolazepam Hydrochloride Injection, Powder, for Solution [US Product Label for Dogs and Cats]. Zoetis Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3ef51363-2236-40aa-bf32-601c9f1c722a — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1265 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.