Reptile · Eublepharis macularius · typical adult weight 0.04–0.10 kg
Tiletamine-Zolazepam is dosed at 3–5 mg/kg IM single dose (frequency not stated) in leopard geckos, per 232. Mitchell MA. Therapeutics. In: Mader DR, ed. Reptile Medicine and Surgery. 2nd ed. St. Louis: Saunders/Elsevier; 2006:631-664. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1413 (2026-08-01, PENDING REVIEW). Tiletamine-Zolazepam is used in leopard geckos for Sedation. Routes documented in leopard geckos: IM. A typical adult leopard gecko weighs 0.04–0.10 kg. ExoticRx lists 1 cited dose rule for Tiletamine-Zolazepam in leopard geckos, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Telazol
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 3–5 mg/kg | single dose (frequency not stated) | Sedation | Weak | 232. Mitchell MA. Therapeutics. In: Mader DR, ed. Reptile Medicine and Surgery. 2nd ed. St. Louis: Saunders/Elsevier; 2006:631-664. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1413 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your leopard gecko's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Tiletamine is a dissociative NMDA antagonist providing anesthesia; zolazepam is a benzodiazepine providing muscle relaxation and reducing emergence reactions.
Controlled substance (CIII). Prolonged recovery in cats (zolazepam component). Causes pain at IM injection site. Cannot titrate once given IM. Avoid in renal/hepatic disease.
Species-specific contraindications and adverse-reaction reports for leopard geckos may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tiletamine-Zolazepam dose range in leopard geckos, with cited source references: IM 3–5 mg/kg single dose (frequency not stated). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tiletamine-Zolazepam in leopard geckos: IM.
Tiletamine-Zolazepam is indicated in leopard geckos for: Sedation.
These are general warnings for Tiletamine-Zolazepam across species; consult the leopard gecko dosing table above for species-specific guidance. Controlled substance (CIII). Prolonged recovery in cats (zolazepam component). Causes pain at IM injection site. Cannot titrate once given IM. Avoid in renal/hepatic disease.
Why a species-specific page? Tiletamine-Zolazepam pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in leopard geckos — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.