Fish · Cyprinus carpio · typical adult weight 0.25–20.00 kg
Propofol is dosed at 2.5–5 mg/L water (immersion bath) Immersion (bath) single immersion to effect in koi, per Oda A, Bailey KM, Lewbart GA, Griffith EH, Posner LP. Physiologic and biochemical assessments of koi (Cyprinus carpio) following immersion in propofol. J Am Vet Med Assoc. 2014;245(11):1286-1291. Propofol is used in koi for General anaesthesia, Anaesthesia. Routes documented in koi: Immersion (bath), by immersion. A typical adult koi weighs 0.25–20.00 kg. ExoticRx lists 2 cited dose rules for Propofol in koi, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rapinovet, PropoFlo
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Immersion (bath) | 2.5–5 mg/L water (immersion bath) | single immersion to effect | Contact time = immerse to effect: mean induction 13.4 +/- 3.3 min at 2.5 mg/L and 3.8 +/- 1.1 min at 5 mg/L (10 mg/L, also tested, induced in 2.3 +/- 0.9 min). Mean recovery 12.9 +/- 8.3 min (2.5 mg/L), 11.0 +/- 6.3 min (5 mg/L) and 18.1 +/- 13.0 min (10 mg/L). All fish recovered satisfactorily from the induction baths. Maintenance, where used, was a SEPARATE 3 mg/L bath and was tested for 20 minutes only. | General anaesthesia | Moderate | Oda A, Bailey KM, Lewbart GA, Griffith EH, Posner LP. Physiologic and biochemical assessments of koi (Cyprinus carpio) following immersion in propofol. J Am Vet Med Assoc. 2014;245(11):1286-1291. doi:10.2460/javma.245.11.1286 https://pubmed.ncbi.nlm.nih.gov/25406710/ |
| by immersion | 2.5–10 mg/l | not stated in the cited source | — | Anaesthesia | Moderate | Ramsey I, ed. BSAVA Small Animal Formulary, 10th ed. Part B: Exotic Pets. Gloucester: British Small Animal Veterinary Association; 2023. p.255.Compilation only — we have not located an independent source that prints this figure. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 2.5 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 2.3 | 2.5 mg/kg IV |
| 3.5–7.5 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 2.3 | 3.5-7.5 mg/kg IV |
| Dose (mg/l) | Route | Source | As printed |
|---|---|---|---|
| 2.5–10 | IMMERSION | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.269 | 2.5-10 mg/l by immersion f. |
| 2.5 |
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Enhances GABA-A receptor activity, producing rapid-onset, ultra-short-acting general anesthesia. Also has some NMDA receptor antagonism.
Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Species-specific contraindications and adverse-reaction reports for koi may differ from canine / feline reference data — consult the primary citations listed with each rule.
Propofol dose ranges in koi, with cited source references: Immersion (bath) 2.5–5 mg/L water (immersion bath) single immersion to effect; by immersion 2.5–10 mg/l not stated in the cited source. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Propofol in koi: Immersion (bath), by immersion.
Cited course lengths for Propofol in koi include: Contact time = immerse to effect: mean induction 13.4 +/- 3.3 min at 2.5 mg/L and 3.8 +/- 1.1 min at 5 mg/L (10 mg/L, also tested, induced in 2.3 +/- 0.9 min). Mean recovery 12.9 +/- 8.3 min (2.5 mg/L), 11.0 +/- 6.3 min (5 mg/L) and 18.1 +/- 13.0 min (10 mg/L). All fish recovered satisfactorily from the induction baths. Maintenance, where used, was a SEPARATE 3 mg/L bath and was tested for 20 minutes only.. Duration depends on the indication — match it to the specific dose rule in the table above.
Propofol is indicated in koi for: General anaesthesia, Anaesthesia.
These are general warnings for Propofol across species; consult the koi dosing table above for species-specific guidance. Respiratory depression/apnea — have intubation equipment ready. No analgesic properties. Hypotension. Repeated use in cats may cause Heinz body formation. Strict aseptic handling (lipid emulsion supports bacterial growth).
Why a species-specific page? Propofol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in koi — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| IMMERSION |
| Carpenter's Exotic Animal Formulary, 6th edTable 2.3 |
| 2.5 mg/L bath × up to 20 min |
| 5 | IMMERSION | Carpenter's Exotic Animal Formulary, 6th edTable 2.3 | 5 mg/L bath |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.