Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Atipamezole is used in rabbits for Medetomidine/dexmedetomidine reversal. Routes documented in rabbits: IM. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Atipamezole in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Antisedan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 5x volume of dexmedetomidine used | Equal volume to medetomidine given | Single dose | Medetomidine/dexmedetomidine reversal | Strong | Morissey JM, Carpenter JW. Appendix: Formulary. In: Quesenberry KE, Orcutt CJ, Mans C, et al. Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.855 (2026-08-01). |
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These ranges are per kg. Enter your rabbit's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Atipamezole dose range in rabbits, with cited source references: IM 5x volume of dexmedetomidine used Equal volume to medetomidine given. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Atipamezole in rabbits: IM.
Cited course lengths for Atipamezole in rabbits include: Single dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Atipamezole is indicated in rabbits for: Medetomidine/dexmedetomidine reversal.
These are general warnings for Atipamezole across species; consult the rabbit dosing table above for species-specific guidance. IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.