Atipamezole for Guinea Pig
Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Atipamezole is used in guinea pig for Medetomidine/dexmedetomidine reversal. Routes documented in guinea pig: IM. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Atipamezole in guinea pig, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Antisedan
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 0 mg/kg | Equal volume to medetomidine | Single dose | Medetomidine/dexmedetomidine reversal | Moderate | Carpenter's Exotic Animal Formulary, 6th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
Side effects & warnings
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for guinea pig may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Antidote drugs with guinea pig dosing
Atipamezole dosing in other species
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pig — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.