Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Atipamezole is used in guinea pigs for Medetomidine/dexmedetomidine reversal. Routes documented in guinea pigs: IM. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Atipamezole in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Antisedan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | IM | Equal volume to medetomidine | Single dose | Medetomidine/dexmedetomidine reversal | Moderate | Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.783 (2026-08-01). |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Atipamezole dose range in guinea pigs, with cited source references: IM IM Equal volume to medetomidine. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Atipamezole in guinea pigs: IM.
Cited course lengths for Atipamezole in guinea pigs include: Single dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Atipamezole is indicated in guinea pigs for: Medetomidine/dexmedetomidine reversal.
These are general warnings for Atipamezole across species; consult the guinea pig dosing table above for species-specific guidance. IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.