Vitamin K1 for Guinea Pig
Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Vitamin K1 is used in guinea pig for Anticoagulant rodenticide poisoning. Routes documented in guinea pig: SC. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Vitamin K1 in guinea pig, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Mephyton, AquaMEPHYTON, Veta-K1
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 1–5 mg/kg | q12h | 4-6 weeks | Anticoagulant rodenticide poisoning | Weak | Carpenter's Exotic Animal Formulary, 6th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Essential cofactor for hepatic carboxylation of clotting factors II, VII, IX, X. Reverses vitamin K-dependent coagulopathy from anticoagulant rodenticides.
Side effects & warnings
Give PO with fatty food (fat-soluble). SC preferred over IM (hematoma risk) or IV (anaphylaxis risk). Long-acting rodenticides (brodifacoum) require 4-6 weeks treatment. Monitor PT.
Species-specific contraindications and adverse-reaction reports for guinea pig may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Antidote drugs with guinea pig dosing
Vitamin K1 dosing in other species
Why a species-specific page? Vitamin K1 pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pig — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.