Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Vitamin K1 is dosed at 1–5 mg/kg SC q12h in guinea pigs, per Ewringmann A, Gloeckner B. Leitsymptome bei Meerschweinchen, Chinchilla und Degu, Enke, Stuttgart, Germany; 2012.; Ewringmann A, Gloeckner B. Leitsymptome bei Hamster, Ratte, Maus und Rennmaus, Enke, Stuttgart, Germany; 2014. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.803 (2026-08-01).. Vitamin K1 is used in guinea pigs for Anticoagulant rodenticide poisoning. Routes documented in guinea pigs: SC. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Vitamin K1 in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Mephyton, AquaMEPHYTON, Veta-K1
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 1–5 mg/kg | q12h | 4-6 weeks | Anticoagulant rodenticide poisoning | Weak | Ewringmann A, Gloeckner B. Leitsymptome bei Meerschweinchen, Chinchilla und Degu, Enke, Stuttgart, Germany; 2012.; Ewringmann A, Gloeckner B. Leitsymptome bei Hamster, Ratte, Maus und Rennmaus, Enke, Stuttgart, Germany; 2014. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.803 (2026-08-01). |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Essential cofactor for hepatic carboxylation of clotting factors II, VII, IX, X. Reverses vitamin K-dependent coagulopathy from anticoagulant rodenticides.
Give PO with fatty food (fat-soluble). SC preferred over IM (hematoma risk) or IV (anaphylaxis risk). Long-acting rodenticides (brodifacoum) require 4-6 weeks treatment. Monitor PT.
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Vitamin K1 dose range in guinea pigs, with cited source references: SC 1–5 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Vitamin K1 in guinea pigs: SC.
Cited course lengths for Vitamin K1 in guinea pigs include: 4-6 weeks. Duration depends on the indication — match it to the specific dose rule in the table above.
Vitamin K1 is indicated in guinea pigs for: Anticoagulant rodenticide poisoning.
These are general warnings for Vitamin K1 across species; consult the guinea pig dosing table above for species-specific guidance. Give PO with fatty food (fat-soluble). SC preferred over IM (hematoma risk) or IV (anaphylaxis risk). Long-acting rodenticides (brodifacoum) require 4-6 weeks treatment. Monitor PT.
Why a species-specific page? Vitamin K1 pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.