Cat · Felis catus · typical adult weight 2.50–7.00 kg
Vitamin K1 is dosed at 2.5–5 mg/kg SC q24h (total daily dose) in cats, per Papich MG, Saunders Handbook of Veterinary Drugs, 4th ed, printed p.638 (corpus PDF p.666) - Phytonadione, Small Animal Dosage, Dogs and Cats: 'Treatment of long-acting rodenticides: 2.5-5 mg/kg/day for 3-4 weeks IM, SQ, or PO.' SC route also printed in Plumb's 9th printed p.1025: 'Initial dose of 2.5 - 5 mg/kg PO or SC' and 'label dosage ... 0.25 - 5 mg/kg SC or IM'. BSAVA 10th ed p.434: 'Known inandione (diphacinone) or unknown anticoagulant toxicity: initially 2.5-5 mg/kg s.c. over several sites.'. Vitamin K1 is used in cats for Anticoagulant rodenticide poisoning. Routes documented in cats: SC. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Vitamin K1 in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Mephyton, AquaMEPHYTON, Veta-K1
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 2.5–5 mg/kg | q24h (total daily dose) | 4-6 weeks for long-acting | Anticoagulant rodenticide poisoning | Strong | Papich MG, Saunders Handbook of Veterinary Drugs, 4th ed, printed p.638 (corpus PDF p.666) - Phytonadione, Small Animal Dosage, Dogs and Cats: 'Treatment of long-acting rodenticides: 2.5-5 mg/kg/day for 3-4 weeks IM, SQ, or PO.' SC route also printed in Plumb's 9th printed p.1025: 'Initial dose of 2.5 - 5 mg/kg PO or SC' and 'label dosage ... 0.25 - 5 mg/kg SC or IM'. BSAVA 10th ed p.434: 'Known inandione (diphacinone) or unknown anticoagulant toxicity: initially 2.5-5 mg/kg s.c. over several sites.' |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Essential cofactor for hepatic carboxylation of clotting factors II, VII, IX, X. Reverses vitamin K-dependent coagulopathy from anticoagulant rodenticides.
Give PO with fatty food (fat-soluble). SC preferred over IM (hematoma risk) or IV (anaphylaxis risk). Long-acting rodenticides (brodifacoum) require 4-6 weeks treatment. Monitor PT.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Vitamin K1 dose range in cats, with cited source references: SC 2.5–5 mg/kg q24h (total daily dose). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Vitamin K1 in cats: SC.
Cited course lengths for Vitamin K1 in cats include: 4-6 weeks for long-acting. Duration depends on the indication — match it to the specific dose rule in the table above.
Vitamin K1 is indicated in cats for: Anticoagulant rodenticide poisoning.
These are general warnings for Vitamin K1 across species; consult the cat dosing table above for species-specific guidance. Give PO with fatty food (fat-soluble). SC preferred over IM (hematoma risk) or IV (anaphylaxis risk). Long-acting rodenticides (brodifacoum) require 4-6 weeks treatment. Monitor PT.
Why a species-specific page? Vitamin K1 pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.