Cat · Felis catus · typical adult weight 2.50–7.00 kg
Edrophonium is dosed at 0.2–0.5 mg/cat (total dose, NOT mg/kg) IV Single IV test dose in cats, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.440, Edrophonium monograph spanning p.440-441; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — located 2026-08-05 in Plumb's 10th ed, Edrophonium monograph, printed p.440-441; the earlier note claiming no held source contained this figure was wrong and has been removed. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Edrophonium is used in cats for Myasthenia gravis (diagnostic). Routes documented in cats: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Edrophonium in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Tensilon, Enlon
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.2–0.5 mg/cat (total dose, NOT mg/kg)max 2 mg total | Single IV test dose | Single dose; brief response confirms diagnosis | Myasthenia gravis (diagnostic) | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.440, Edrophonium monograph spanning p.440-441; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — located 2026-08-05 in Plumb's 10th ed, Edrophonium monograph, printed p.440-441; the earlier note claiming no held source contained this figure was wrong and has been removed. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/animal) | Route | Source | As printed |
|---|---|---|---|
| 0.25–0.5 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.308 | • 0.11-0.22 mg/kg IV (maximum dose • 0.25-0.5 mg/cat IV. |
| 1–1.25 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.310 | • 1-1.25 mg/cat/day PO. |
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 6 | IM |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Ultra-short-acting reversible acetylcholinesterase inhibitor used diagnostically. Transient improvement in myasthenia gravis confirms the diagnosis.
Very short duration (5-10 minutes). Have atropine ready for cholinergic reactions. False negatives possible. Use IV only with monitoring.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Edrophonium dose range in cats, with cited source references: IV 0.2–0.5 mg/cat (total dose, NOT mg/kg) Single IV test dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Edrophonium in cats: IV.
Cited course lengths for Edrophonium in cats include: Single dose; brief response confirms diagnosis. Duration depends on the indication — match it to the specific dose rule in the table above.
Edrophonium is indicated in cats for: Myasthenia gravis (diagnostic).
These are general warnings for Edrophonium across species; consult the cat dosing table above for species-specific guidance. Very short duration (5-10 minutes). Have atropine ready for cholinergic reactions. False negatives possible. Use IV only with monitoring.
Why a species-specific page? Edrophonium pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.159 |
| 0.25-0.5 mg total dose/cat i.v. Doses >6 mg/kg have been experimentally reported in cats but will result in bradycardia and are not |
| 0.04 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.159 | es, for a positive test. Atropine should be available (0.04 mg/kg) to control cholinergic side effects (e.g. salivation, urination). • Atrial tachyc |
| 0.11–0.22 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.308 | • 0.11-0.22 mg/kg IV (maximum dose • 0.25-0.5 mg/cat IV. |
| 0.25–0.5 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.310 | • 0.25-0.5 mg/kg q12-24h PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.