Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Edrophonium is used in dog for Myasthenia gravis (diagnostic Tensilon test). Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Edrophonium in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Tensilon, Enlon
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.1–0.2 mg/kg | Single IV test dose | Single diagnostic dose; observe for 5-10 minutes for clinical improvement | Myasthenia gravis (diagnostic Tensilon test) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed; ACVIM Consensus on MG |
Absolute dose ceiling, regardless of body weight: 5 mg total (IV).
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Ultra-short-acting reversible acetylcholinesterase inhibitor used diagnostically. Transient improvement in myasthenia gravis confirms the diagnosis.
Very short duration (5-10 minutes). Have atropine ready for cholinergic reactions. False negatives possible. Use IV only with monitoring.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Edrophonium pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.