Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Lipid Emulsion (ILE) 20% is dosed at 1.5 ml/kg IV Bolus 1min, CRI 0.25ml/kg/min x30-60m in dogs, per Robben JH, Dijkman MA. Lipid therapy for intoxications. Vet Clin North Am Small Animal Pract. 2017;47(2):435-450. doi:10.1016/j.cvsm.2016.10.018 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.795 (2026-08-01).. Lipid Emulsion (ILE) 20% is used in dogs for Local anesthetic systemic toxicity (LAST)/Lipophilic drug overdose. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Lipid Emulsion (ILE) 20% in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Intralipid, ClinOleic
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 1.5 ml/kg | Bolus 1min, CRI 0.25ml/kg/min x30-60m | Bolus then 30-60 minute infusion; may repeat bolus x1 | Local anesthetic systemic toxicity (LAST)/Lipophilic drug overdose | Moderate | Robben JH, Dijkman MA. Lipid therapy for intoxications. Vet Clin North Am Small Animal Pract. 2017;47(2):435-450. doi:10.1016/j.cvsm.2016.10.018 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.795 (2026-08-01). |
One of the cited rules is a continuous-rate-infusion regimen: IV 1.5 ml/kg Bolus 1min, CRI 0.25ml/kg/min x30-60m. CRI regimens are delivered as a continuous infusion rather than discrete doses — verify the rate against the cited source before use.
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Creates a lipid sink in plasma that sequesters lipophilic drugs away from target tissues. May also enhance mitochondrial energy production in cardiac tissue.
For local anesthetic systemic toxicity (LAST), permethrin toxicity, and other lipophilic drug overdoses. Pancreatitis risk. Interferes with lab tests. Use 20% emulsion only.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Lipid Emulsion (ILE) 20% dose range in dogs, with cited source references: IV 1.5 ml/kg Bolus 1min, CRI 0.25ml/kg/min x30-60m. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Lipid Emulsion (ILE) 20% in dogs: IV.
Cited course lengths for Lipid Emulsion (ILE) 20% in dogs include: Bolus then 30-60 minute infusion; may repeat bolus x1. Duration depends on the indication — match it to the specific dose rule in the table above.
Lipid Emulsion (ILE) 20% is indicated in dogs for: Local anesthetic systemic toxicity (LAST)/Lipophilic drug overdose.
These are general warnings for Lipid Emulsion (ILE) 20% across species; consult the dog dosing table above for species-specific guidance. For local anesthetic systemic toxicity (LAST), permethrin toxicity, and other lipophilic drug overdoses. Pancreatitis risk. Interferes with lab tests. Use 20% emulsion only.
Why a species-specific page? Lipid Emulsion (ILE) 20% pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.