Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Lipid Emulsion (ILE) 20% is used in dog for Local anesthetic systemic toxicity (LAST)/Lipophilic drug overdose. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Lipid Emulsion (ILE) 20% in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Intralipid, ClinOleic
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 1.5 ml/kg | Bolus 1min, CRI 0.25ml/kg/min x30-60m | Bolus then 30-60 minute infusion; may repeat bolus x1 | Local anesthetic systemic toxicity (LAST)/Lipophilic drug overdose | Moderate | VECCS Guidelines; AACT Consensus on ILE |
One of the cited rules is a continuous-rate-infusion regimen: IV 1.5 ml/kg Bolus 1min, CRI 0.25ml/kg/min x30-60m. CRI regimens are delivered as a continuous infusion rather than discrete doses — verify the rate against the cited source before use.
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Creates a lipid sink in plasma that sequesters lipophilic drugs away from target tissues. May also enhance mitochondrial energy production in cardiac tissue.
For local anesthetic systemic toxicity (LAST), permethrin toxicity, and other lipophilic drug overdoses. Pancreatitis risk. Interferes with lab tests. Use 20% emulsion only.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Lipid Emulsion (ILE) 20% pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.