Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Atipamezole is used in dogs for Medetomidine/dexmedetomidine reversal. Routes documented in dogs: IM. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Atipamezole in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Antisedan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | IM only | Equal volume to medetomidine or 5x dexmedetomidine | Single dose | Medetomidine/dexmedetomidine reversal | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Atipamezole dose range in dogs, with cited source references: IM IM only Equal volume to medetomidine or 5x dexmedetomidine. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Atipamezole in dogs: IM.
Cited course lengths for Atipamezole in dogs include: Single dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Atipamezole is indicated in dogs for: Medetomidine/dexmedetomidine reversal.
These are general warnings for Atipamezole across species; consult the dog dosing table above for species-specific guidance. IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.