Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Digoxin Immune Fab is used in dogs for Digoxin toxicosis. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Digoxin Immune Fab in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Digibind, DigiFab
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | See the cited source for the printed regimen | Based on digoxin body load | Single infusion | Digoxin toxicosis | Moderate | Pao-Franco A, Hammond TN, Weatherton LK, De Clementi C, Forney SD. Successful use of digoxin-specific immune Fab in the treatment of severe Nerium oleander toxicosis in a dog. J Vet Emerg Crit Care. 2017;27(5):596-604. doi:10.1111/vec.12634 — Verified against Riviere & Papich, Veterinary Pharmacology and Therapeutics, 10th Ed, p.534 (2026-08-01). — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855; Veterinary Pharmacology and Therapeutics — ISBN 9781118855829, https://openlibrary.org/isbn/9781118855829 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mcg/kg) | Route | Source | As printed |
|---|---|---|---|
| 3.5 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.140 | 2.5-3.5 μg (micrograms)/kg p.o. q12h based on lean body weight (decrease dose by 10% for elixir). Maximum dose 0.25 |
| 2.2–4.4 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.140 | eutic levels. Only use i.v. if essentially indicated: 2.2-4.4 μg/kg i.v. q12h |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Ovine digoxin-specific Fab antibody fragments that bind free digoxin/digitoxin with high affinity, preventing receptor binding.
Specific antidote for digoxin/digitoxin toxicosis. Very expensive. Dose based on amount of digoxin ingested or serum level. Effect within 30 minutes IV. Rarely available in veterinary settings.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Digoxin Immune Fab dose range in dogs, with cited source references: IV See the cited source for the printed regimen Based on digoxin body load. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Digoxin Immune Fab in dogs: IV.
Cited course lengths for Digoxin Immune Fab in dogs include: Single infusion. Duration depends on the indication — match it to the specific dose rule in the table above.
Digoxin Immune Fab is indicated in dogs for: Digoxin toxicosis.
These are general warnings for Digoxin Immune Fab across species; consult the dog dosing table above for species-specific guidance. Specific antidote for digoxin/digitoxin toxicosis. Very expensive. Dose based on amount of digoxin ingested or serum level. Effect within 30 minutes IV. Rarely available in veterinary settings.
Why a species-specific page? Digoxin Immune Fab pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.