Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Flumazenil is used in dog for Benzodiazepine reversal. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Flumazenil in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Romazicon
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.01–0.02 mg/kg | IV bolus | May repeat in 20 min | Benzodiazepine reversal | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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Competitive benzodiazepine receptor antagonist at GABA-A receptor. Reverses sedation, respiratory depression, and anxiolysis from benzodiazepines.
Short duration (45-60 min) — resedation risk with long-acting benzodiazepines. May precipitate seizures in benzodiazepine-dependent patients or when benzos given for seizure control.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Flumazenil pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.