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Flumazenil for Blue-tongue Skinks

Reptile · Tiliqua scincoides · typical adult weight 0.25–0.60 kg

Flumazenil is dosed at 0.05 mg/kg SC 60 min after induction (if not recovered) in blue-tongue skinks, per Evaluating the Physiologic Effects of Alfaxalone, Dexmedetomidine, and Midazolam Combinations in Common Blue-Tongued Skinks (Tiliqua scincoides). Animals 2024, 14(18), 2636. DOI 10.3390/ani14182636; PMID 39335227; PMCID PMC11429061. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC11429061/. Flumazenil is used in blue-tongue skinks for Reversal of midazolam in skinks not recovered. Routes documented in blue-tongue skinks: SC. A typical adult blue-tongue skink weighs 0.25–0.60 kg. ExoticRx lists 1 cited dose rule for Flumazenil in blue-tongue skinks, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Romazicon

Dose ranges

RouteDoseFrequencyIndicationEvidenceSource
SC0.05 mg/kg60 min after induction (if not recovered)Reversal of midazolam in skinks not recoveredWeakEvaluating the Physiologic Effects of Alfaxalone, Dexmedetomidine, and Midazolam Combinations in Common Blue-Tongued Skinks (Tiliqua scincoides). Animals 2024, 14(18), 2636. DOI 10.3390/ani14182636; PMID 39335227; PMCID PMC11429061. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC11429061/

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Mechanism of action

Competitive benzodiazepine receptor antagonist at GABA-A receptor. Reverses sedation, respiratory depression, and anxiolysis from benzodiazepines.

Side effects & warnings

Short duration (45-60 min) — resedation risk with long-acting benzodiazepines. May precipitate seizures in benzodiazepine-dependent patients or when benzos given for seizure control.

Species-specific contraindications and adverse-reaction reports for blue-tongue skinks may differ from canine / feline reference data — consult the primary citations listed with each rule.

Frequently asked questions

What is the dose of Flumazenil for Blue-tongue Skinks?

Flumazenil dose range in blue-tongue skinks, with cited source references: SC 0.05 mg/kg 60 min after induction (if not recovered).

How is Flumazenil administered in Blue-tongue Skinks?

Documented routes for Flumazenil in blue-tongue skinks: SC.

What conditions does Flumazenil treat in Blue-tongue Skinks?

Flumazenil is indicated in blue-tongue skinks for: Reversal of midazolam in skinks not recovered.

What are the side effects of Flumazenil in Blue-tongue Skinks?

These are general warnings for Flumazenil across species; consult the blue-tongue skink dosing table above for species-specific guidance. Short duration (45-60 min) — resedation risk with long-acting benzodiazepines. May precipitate seizures in benzodiazepine-dependent patients or when benzos given for seizure control.

Other Antidote drugs with blue-tongue skink dosing

Flumazenil dosing in other species

Why a species-specific page? Flumazenil pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in blue-tongue skinks — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.