Atipamezole for Blue-tongue Skinks
Reptile · Tiliqua scincoides · typical adult weight 0.25–0.60 kg
Atipamezole is dosed at 0.5 mg/kg SC 60 min after induction (if not recovered) in blue-tongue skinks, per Evaluating the Physiologic Effects of Alfaxalone, Dexmedetomidine, and Midazolam Combinations in Common Blue-Tongued Skinks (Tiliqua scincoides). Animals 2024, 14(18), 2636. DOI 10.3390/ani14182636; PMID 39335227; PMCID PMC11429061. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC11429061/. Atipamezole is used in blue-tongue skinks for Reversal of dexmedetomidine in skinks not recovered. Routes documented in blue-tongue skinks: SC. A typical adult blue-tongue skink weighs 0.25–0.60 kg. ExoticRx lists 1 cited dose rule for Atipamezole in blue-tongue skinks, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Antisedan
Dose ranges
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC | 0.5 mg/kg | 60 min after induction (if not recovered) | Reversal of dexmedetomidine in skinks not recovered | Weak | Evaluating the Physiologic Effects of Alfaxalone, Dexmedetomidine, and Midazolam Combinations in Common Blue-Tongued Skinks (Tiliqua scincoides). Animals 2024, 14(18), 2636. DOI 10.3390/ani14182636; PMID 39335227; PMCID PMC11429061. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC11429061/ |
Need the exact dose for your patient?
These ranges are per kg. Enter your blue-tongue skink's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
Side effects & warnings
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for blue-tongue skinks may differ from canine / feline reference data — consult the primary citations listed with each rule.
Frequently asked questions
What is the dose of Atipamezole for Blue-tongue Skinks?
Atipamezole dose range in blue-tongue skinks, with cited source references: SC 0.5 mg/kg 60 min after induction (if not recovered).
How is Atipamezole administered in Blue-tongue Skinks?
Documented routes for Atipamezole in blue-tongue skinks: SC.
What conditions does Atipamezole treat in Blue-tongue Skinks?
Atipamezole is indicated in blue-tongue skinks for: Reversal of dexmedetomidine in skinks not recovered.
What are the side effects of Atipamezole in Blue-tongue Skinks?
These are general warnings for Atipamezole across species; consult the blue-tongue skink dosing table above for species-specific guidance. IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Other Antidote drugs with blue-tongue skink dosing
Atipamezole dosing in other species
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in blue-tongue skinks — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.